Evaluation of the proliferation marker Ki-67 in gliomas: Interobserver variability and digital quantification

Evaluation of the proliferation marker Ki-67 in gliomas: Interobserver variability and digital quantification

Abstract Background The Ki-67 Labelling Index (LI) is used as an ancillary tool in glioma diagnostics. Interobserver variability has been reported and no precise guidelines are available. Nor is it known whether novel digital approaches would be an advantage. Our aim was to evaluate the inter- and i...

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Bibliographic Details
Main Authors: Ljudmilla A. G. Nielsen, Julie A. Bangsø, Kim H. Lindahl, Rikke H. Dahlrot, Jacob v. B. Hjelmborg, Steinbjørn Hansen, Bjarne W. Kristensen
Format: Article
Language:English
Published: BMC 2018-06-01
Series:Diagnostic Pathology
Subjects:
Glioblastoma
Astrocytoma
Digital analysis
Whole slides
Labelling index
Online Access:http://link.springer.com/article/10.1186/s13000-018-0711-2

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