Partners in crime: The feedback loop between metabolic reprogramming and immune checkpoints in the tumor microenvironment

Partners in crime: The feedback loop between metabolic reprogramming and immune checkpoints in the tumor microenvironment

The tumor microenvironment (TME) is a complex and constantly changing cellular system composed of heterogeneous populations of tumor cells and non-transformed stromal cells, such as stem cells, fibroblasts, endothelial cells, pericytes, adipocytes, and innate and adaptive immune cells. Tumor, stroma...

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Bibliographic Details
Main Authors: Jesus J. Benito-Lopez, Mario Marroquin-Muciño, Mario Perez-Medina, Rodolfo Chavez-Dominguez, Dolores Aguilar-Cazares, Miriam Galicia-Velasco, Jose S. Lopez-Gonzalez
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Oncology
Subjects:
tumor microenvironment
metabolic reprogramming
immune cells
tumor cells
glucose and lactate
exogen amino acids
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.1101503/full

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