The overexpression of COX 2 in Wilms’ tumor
Cyclooxygenase 2 has become an important pharmacological target in anticancer therapy due to the over expression of COX 2 in pathological conditions. Wilms’ tumor is a common kidney cancer in children which has shown an increase in COX 2 enzyme level. Here we reviewed various articles that considere...
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| פורמט: | Article |
| שפה: | English |
| יצא לאור: |
Mashhad University of Medical Sciences
2014-02-01
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| סדרה: | Reviews in Clinical Medicine |
| נושאים: | |
| גישה מקוונת: | https://rcm.mums.ac.ir/article_2207_48fb82958431523c7a61ae21a3844726.pdf |
| סיכום: | Cyclooxygenase 2 has become an important pharmacological target in anticancer therapy due to the over expression of COX 2 in pathological conditions. Wilms’ tumor is a common kidney cancer in children which has shown an increase in COX 2 enzyme level. Here we reviewed various articles that considered the cyclooxygenase 2 changes specifically in Wilms’ tumor regarding the mechanisms of action and inhibitors of COX 2. |
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| ISSN: | 2345-6256 2345-6892 |