Light and Scanning Electron Microscopy of Red Blood Cells From Humans and Animal Species Providing Insights into Molecular Cell Biology
We reviewed the many discoveries in cell biology, made since the 17th century, which have been based on red blood cells (RBCs). The advances in molecular and structural biology in the past 40 years have enabled the discovery with these cells, most notably, of the first water channel protein (WCP) ca...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-07-01
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| Series: | Frontiers in Physiology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fphys.2022.838071/full |
| _version_ | 1811237522076860416 |
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| author | Gheorghe Benga Gheorghe Benga Guy Cox |
| author_facet | Gheorghe Benga Gheorghe Benga Guy Cox |
| author_sort | Gheorghe Benga |
| collection | DOAJ |
| description | We reviewed the many discoveries in cell biology, made since the 17th century, which have been based on red blood cells (RBCs). The advances in molecular and structural biology in the past 40 years have enabled the discovery with these cells, most notably, of the first water channel protein (WCP) called today aquaporin1 (AQP1). The main aim of our work reviewed was to examine by light and electron microscopy a very wide range of RBCs from reptiles, birds, monotremes, marsupials and placentals, in order to estimate from these images the RBC cell volume and surface area. The diffusional water permeability of the RBC membrane from these species has further been measured with a nuclear magnetic resonance (NMR) spectroscopy technique. The significance of the observed permeability of RBCs to water and possible influences on the whole body are discussed. |
| first_indexed | 2024-04-12T12:24:57Z |
| format | Article |
| id | doaj.art-f8d00cebc0d74a49b32802640bf69717 |
| institution | Directory Open Access Journal |
| issn | 1664-042X |
| language | English |
| last_indexed | 2024-04-12T12:24:57Z |
| publishDate | 2022-07-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Physiology |
| spelling | doaj.art-f8d00cebc0d74a49b32802640bf697172022-12-22T03:33:12ZengFrontiers Media S.A.Frontiers in Physiology1664-042X2022-07-011310.3389/fphys.2022.838071838071Light and Scanning Electron Microscopy of Red Blood Cells From Humans and Animal Species Providing Insights into Molecular Cell BiologyGheorghe Benga0Gheorghe Benga1Guy Cox2Romanian Academy, Cluj-Napoca, RomaniaSchool of Life and Environmental Sciences, Faculty of Science, University of Sydney, Darlington, NSW, AustraliaAustralian Centre for Microscopy & Microanalysis, University of Sydney, Darlington, NSW, AustraliaWe reviewed the many discoveries in cell biology, made since the 17th century, which have been based on red blood cells (RBCs). The advances in molecular and structural biology in the past 40 years have enabled the discovery with these cells, most notably, of the first water channel protein (WCP) called today aquaporin1 (AQP1). The main aim of our work reviewed was to examine by light and electron microscopy a very wide range of RBCs from reptiles, birds, monotremes, marsupials and placentals, in order to estimate from these images the RBC cell volume and surface area. The diffusional water permeability of the RBC membrane from these species has further been measured with a nuclear magnetic resonance (NMR) spectroscopy technique. The significance of the observed permeability of RBCs to water and possible influences on the whole body are discussed.https://www.frontiersin.org/articles/10.3389/fphys.2022.838071/fullerythrocytemicroscopymarsupialmonotremeplacental mammalNMR |
| spellingShingle | Gheorghe Benga Gheorghe Benga Guy Cox Light and Scanning Electron Microscopy of Red Blood Cells From Humans and Animal Species Providing Insights into Molecular Cell Biology Frontiers in Physiology erythrocyte microscopy marsupial monotreme placental mammal NMR |
| title | Light and Scanning Electron Microscopy of Red Blood Cells From Humans and Animal Species Providing Insights into Molecular Cell Biology |
| title_full | Light and Scanning Electron Microscopy of Red Blood Cells From Humans and Animal Species Providing Insights into Molecular Cell Biology |
| title_fullStr | Light and Scanning Electron Microscopy of Red Blood Cells From Humans and Animal Species Providing Insights into Molecular Cell Biology |
| title_full_unstemmed | Light and Scanning Electron Microscopy of Red Blood Cells From Humans and Animal Species Providing Insights into Molecular Cell Biology |
| title_short | Light and Scanning Electron Microscopy of Red Blood Cells From Humans and Animal Species Providing Insights into Molecular Cell Biology |
| title_sort | light and scanning electron microscopy of red blood cells from humans and animal species providing insights into molecular cell biology |
| topic | erythrocyte microscopy marsupial monotreme placental mammal NMR |
| url | https://www.frontiersin.org/articles/10.3389/fphys.2022.838071/full |
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