Effect of Caffeine on the retention and retrieval of memory in mice
Objective: Caffeine consumption may reinforce and/or deteriorate memory and learning this is related to the dose of caffeine. The effect of caffeine on retention and retrieval of memory in mice, by using of passive avoidance learning was investigated. Methods: For this purpose after weighing, codin...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Babol University of Medical Sciences
2000-10-01
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| Series: | Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul |
| Subjects: | |
| Online Access: | http://jbums.org/article-1-2889-en.html |
| _version_ | 1818826776468520960 |
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| author | A Arzi AA Naderi |
| author_facet | A Arzi AA Naderi |
| author_sort | A Arzi |
| collection | DOAJ |
| description | Objective: Caffeine consumption may reinforce and/or deteriorate memory and learning this is related to the dose of caffeine. The effect of caffeine on retention and retrieval of memory in mice, by using of passive avoidance learning was investigated. Methods: For this purpose after weighing, coding and grouping, the mice were examined as follows: a) Test group that received electric shock and caffeine (5 mg/kg). B) Control group that received electric shock and saline (IP). C) Shame group that only received electric shock. The latency period for both retention and retrieval tests of memory in all three groups of mice were measured. Caffeine was injected immediately after an electric shock in the retention test of memory and 23,30´ hours after electric shock in the retrieval test of memory. Findings: Obtained results indicate that caffeine (5 mg/kg) reinforced retention of memory, but in comparison with control group, there was no significant difference and also it caused to reinforces retrieval of memory, but in comparison with control group, there was a significant difference. Conclusion: The results indicate that caffeine (5 mg/kg) has no effect on retention of memory, but it reinforces the retrieval of memory. |
| first_indexed | 2024-12-19T00:33:02Z |
| format | Article |
| id | doaj.art-f8d1bf3e283a410ea661034670a9553f |
| institution | Directory Open Access Journal |
| issn | 1561-4107 2251-7170 |
| language | English |
| last_indexed | 2024-12-19T00:33:02Z |
| publishDate | 2000-10-01 |
| publisher | Babol University of Medical Sciences |
| record_format | Article |
| series | Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul |
| spelling | doaj.art-f8d1bf3e283a410ea661034670a9553f2022-12-21T20:45:00ZengBabol University of Medical SciencesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul1561-41072251-71702000-10-01241216Effect of Caffeine on the retention and retrieval of memory in miceA Arzi0AA Naderi1 Objective: Caffeine consumption may reinforce and/or deteriorate memory and learning this is related to the dose of caffeine. The effect of caffeine on retention and retrieval of memory in mice, by using of passive avoidance learning was investigated. Methods: For this purpose after weighing, coding and grouping, the mice were examined as follows: a) Test group that received electric shock and caffeine (5 mg/kg). B) Control group that received electric shock and saline (IP). C) Shame group that only received electric shock. The latency period for both retention and retrieval tests of memory in all three groups of mice were measured. Caffeine was injected immediately after an electric shock in the retention test of memory and 23,30´ hours after electric shock in the retrieval test of memory. Findings: Obtained results indicate that caffeine (5 mg/kg) reinforced retention of memory, but in comparison with control group, there was no significant difference and also it caused to reinforces retrieval of memory, but in comparison with control group, there was a significant difference. Conclusion: The results indicate that caffeine (5 mg/kg) has no effect on retention of memory, but it reinforces the retrieval of memory.http://jbums.org/article-1-2889-en.htmlcaffeinememoryelectric shockretention of memoryretrieval of memory |
| spellingShingle | A Arzi AA Naderi Effect of Caffeine on the retention and retrieval of memory in mice Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul caffeine memory electric shock retention of memory retrieval of memory |
| title | Effect of Caffeine on the retention and retrieval of memory in mice |
| title_full | Effect of Caffeine on the retention and retrieval of memory in mice |
| title_fullStr | Effect of Caffeine on the retention and retrieval of memory in mice |
| title_full_unstemmed | Effect of Caffeine on the retention and retrieval of memory in mice |
| title_short | Effect of Caffeine on the retention and retrieval of memory in mice |
| title_sort | effect of caffeine on the retention and retrieval of memory in mice |
| topic | caffeine memory electric shock retention of memory retrieval of memory |
| url | http://jbums.org/article-1-2889-en.html |
| work_keys_str_mv | AT aarzi effectofcaffeineontheretentionandretrievalofmemoryinmice AT aanaderi effectofcaffeineontheretentionandretrievalofmemoryinmice |