Studies on the Complexation of Platinum(II) by Some 4-Nitroisoxazoles and Testing the Cytotoxic Activity of the Resulting Complexes

Studies on the Complexation of Platinum(II) by Some 4-Nitroisoxazoles and Testing the Cytotoxic Activity of the Resulting Complexes

Two novel platinum(II) complexes (<b>1</b> and <b>2</b>) were synthesized by the reaction of the appropriate 3,5-dimethyl-4-nitroisoxazole with K<sub>2</sub>PtCl<sub>4</sub> and characterized by elemental analysis, ESI MS spectrometry, <sup>1<...

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Bibliographic Details
Main Authors: Henryk Mastalarz, Agnieszka Mastalarz, Joanna Wietrzyk, Magdalena Milczarek, Andrzej Kochel, Andrzej Regiec
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Molecules
Subjects:
4-nitroisoxazoles-Pt(II) complexes
synthesis
structural analysis
LogP
cellular platinum uptake
cytotoxic activity
Online Access:https://www.mdpi.com/1420-3049/28/3/1284

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