Breaking Barriers to an AIDS Model with Macaque-Tropic HIV-1 Derivatives

Breaking Barriers to an AIDS Model with Macaque-Tropic HIV-1 Derivatives

The development of an animal model of human immunodeficiency virus type 1 (HIV-1)/AIDS that is suitable for preclinical testing of antiretroviral therapy, vaccines, curative strategies, and studies of pathogenesis has been hampered by the human-specific tropism of HIV-1. Although simian immunodefici...

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Bibliographic Details
Main Authors:	Jason T. Kimata, Hongmei Ruan, Rajesh Thippeshappa
Format:	Article
Language:	English
Published:	MDPI AG 2012-07-01
Series:	Biology
Subjects:	HIV-1 SIV Macaca nemestrina AIDS cross-species tropism innate restriction
Online Access:	http://www.mdpi.com/2079-7737/1/2/134

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