Massive expression of cysteine-containing proteins causes abnormal elongation of yeast cells by perturbing the proteasome

AbstractThe enhanced green fluorescent protein (EGFP) is considered to be a harmless protein because the critical expression level that causes growth defects is higher than that of other proteins. Here, we found that overexpression of EGFP, but not a glycolytic protein Gpm1, triggere...

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Bibliographic Details
Main Authors: Shotaro Namba, Hisaaki Kato, Shuji Shigenobu, Takashi Makino, Hisao Moriya
Format: Article
Language:English
Published: Oxford University Press 2022-04-01
Series:G3: Genes, Genomes, Genetics
Online Access:https://academic.oup.com/g3journal/article-lookup/doi/10.1093/g3journal/jkac106
Description
Summary:AbstractThe enhanced green fluorescent protein (EGFP) is considered to be a harmless protein because the critical expression level that causes growth defects is higher than that of other proteins. Here, we found that overexpression of EGFP, but not a glycolytic protein Gpm1, triggered the cell elongation phenotype in the budding yeast Saccharomyces cerevisiaeSchizosaccharomyces pombeSHOTA
ISSN:2160-1836