A streamlined strain engineering workflow with genome-wide screening detects enhanced protein secretion in Komagataella phaffii
A high-throughput workflow involving a streamlined genome-wide screen improves protein production in the non-conventional yeast, Komagataella phaffii, following adaptive laboratory evolution.
Bibliographic Details
Main Authors: |
Yoichiro Ito,
Misa Ishigami,
Goro Terai,
Yasuyuki Nakamura,
Noriko Hashiba,
Teruyuki Nishi,
Hikaru Nakazawa,
Tomohisa Hasunuma,
Kiyoshi Asai,
Mitsuo Umetsu,
Jun Ishii,
Akihiko Kondo |
Format: | Article
|
Language: | English |
Published: |
Nature Portfolio
2022-06-01
|
Series: | Communications Biology
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Online Access: | https://doi.org/10.1038/s42003-022-03475-w
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