Quantitative ultrasonography as a tool for the evaluation of breast tumor response to neoadjuvant chemotherapy

Neoadjuvant chemotherapy is increasingly becoming the first treatment step in breast cancer. Despite the enormous advantages of this therapy, it is a method characterized by a high level of toxicity and thus carries a huge burden for the patient. Therefore, it is highly desirable to begin monitoring...

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Main Authors: Piotrzkowska-Wróblewska Hanna, Dobruch-Sobczak Katarzyna, Litniewski Jerzy
Format: Article
Language:English
Published: Sciendo 2022-04-01
Series:Journal of Ultrasonography
Subjects:
Online Access:https://doi.org/10.15557/JoU.2022.0015
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author Piotrzkowska-Wróblewska Hanna
Dobruch-Sobczak Katarzyna
Litniewski Jerzy
author_facet Piotrzkowska-Wróblewska Hanna
Dobruch-Sobczak Katarzyna
Litniewski Jerzy
author_sort Piotrzkowska-Wróblewska Hanna
collection DOAJ
description Neoadjuvant chemotherapy is increasingly becoming the first treatment step in breast cancer. Despite the enormous advantages of this therapy, it is a method characterized by a high level of toxicity and thus carries a huge burden for the patient. Therefore, it is highly desirable to begin monitoring the patient’s response to treatment at an earlier stage. Currently, apart from traditional imaging methods, a completely new technique (in the context of monitoring the outcomes of chemotherapy), called quantitative ultrasound, is gaining popularity. It is a method based on the exact same ultrasound echoes as in traditional ultrasound imaging. The innovative approach of the method is that these echoes are not used for visualization but to characterize the condition of the tissue by parameterizing it with the aid of ultrasound biomarkers. The biomarkers make it possible to assess the state of the tissue at the microscopic level, and thus evaluate changes occurring in the tissue under the influence of treatment at a very early treatment stage. The present paper aims to familiarize the reader with the physical foundations of this method as well as present the latest results of related research.
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spelling doaj.art-f8df5b309cce47c48f540964191c5dbb2022-12-22T03:40:28ZengSciendoJournal of Ultrasonography2451-070X2022-04-012289869210.15557/JoU.2022.0015Quantitative ultrasonography as a tool for the evaluation of breast tumor response to neoadjuvant chemotherapyPiotrzkowska-Wróblewska Hanna0Dobruch-Sobczak Katarzyna1Litniewski Jerzy2Department of Ultrasound, Institute of Fundamental Technological Research Polish Academy of Sciences, Warsaw, PolandRadiology Department II, Maria Sklodowska-Curie National Research Institute of Oncology, Warsaw, PolandDepartment of Ultrasound, Institute of Fundamental Technological Research Polish Academy of Sciences, Warsaw, PolandNeoadjuvant chemotherapy is increasingly becoming the first treatment step in breast cancer. Despite the enormous advantages of this therapy, it is a method characterized by a high level of toxicity and thus carries a huge burden for the patient. Therefore, it is highly desirable to begin monitoring the patient’s response to treatment at an earlier stage. Currently, apart from traditional imaging methods, a completely new technique (in the context of monitoring the outcomes of chemotherapy), called quantitative ultrasound, is gaining popularity. It is a method based on the exact same ultrasound echoes as in traditional ultrasound imaging. The innovative approach of the method is that these echoes are not used for visualization but to characterize the condition of the tissue by parameterizing it with the aid of ultrasound biomarkers. The biomarkers make it possible to assess the state of the tissue at the microscopic level, and thus evaluate changes occurring in the tissue under the influence of treatment at a very early treatment stage. The present paper aims to familiarize the reader with the physical foundations of this method as well as present the latest results of related research.https://doi.org/10.15557/JoU.2022.0015quantitative ultrasoundbreast cancerneoadjuvant chemotherapy
spellingShingle Piotrzkowska-Wróblewska Hanna
Dobruch-Sobczak Katarzyna
Litniewski Jerzy
Quantitative ultrasonography as a tool for the evaluation of breast tumor response to neoadjuvant chemotherapy
Journal of Ultrasonography
quantitative ultrasound
breast cancer
neoadjuvant chemotherapy
title Quantitative ultrasonography as a tool for the evaluation of breast tumor response to neoadjuvant chemotherapy
title_full Quantitative ultrasonography as a tool for the evaluation of breast tumor response to neoadjuvant chemotherapy
title_fullStr Quantitative ultrasonography as a tool for the evaluation of breast tumor response to neoadjuvant chemotherapy
title_full_unstemmed Quantitative ultrasonography as a tool for the evaluation of breast tumor response to neoadjuvant chemotherapy
title_short Quantitative ultrasonography as a tool for the evaluation of breast tumor response to neoadjuvant chemotherapy
title_sort quantitative ultrasonography as a tool for the evaluation of breast tumor response to neoadjuvant chemotherapy
topic quantitative ultrasound
breast cancer
neoadjuvant chemotherapy
url https://doi.org/10.15557/JoU.2022.0015
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