Optimisation of user-selectable volumetric modulated arc therapy (VMAT) planning parameters: A study of VMAT arcs for prostate and head-and-neck cancers
Objective: To evaluate different VMAT planning techniques for a multi-leaf collimator (MLC)providing maximum aperture of 21 × 16 cm². Methods: A VMAT planning study of nine prostate and nine head-and-neck cancer patients was carried out. The patients were previously treated with Intensity Modulat...
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| Format: | Article |
| Language: | English |
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Pakistan Medical Association
2021-11-01
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| Series: | Journal of the Pakistan Medical Association |
| Online Access: | https://www.ojs.jpma.org.pk/index.php/public_html/article/view/532 |
| _version_ | 1797820761584435200 |
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| author | Ghulam Murtaza Zaheer Abbas Gillani Shahid Mehmood Jalil Ur Rehman Ehsan Ullah Khan |
| author_facet | Ghulam Murtaza Zaheer Abbas Gillani Shahid Mehmood Jalil Ur Rehman Ehsan Ullah Khan |
| author_sort | Ghulam Murtaza |
| collection | DOAJ |
| description |
Objective: To evaluate different VMAT planning techniques for a multi-leaf collimator (MLC)providing maximum aperture of 21 × 16 cm².
Methods: A VMAT planning study of nine prostate and nine head-and-neck cancer patients was carried out. The patients were previously treated with Intensity Modulated Radiotherapy (IMRT) technique during 2014-15, at radiation oncology SanBortolo Hospital, Vicenza, Italy. Three VMAT plans for each of prostate and head-and-neck cancer patient were optimized using Pinnacle treatment planning system for 6MV photon beam from ElektaSynergyS®Linac system. Single arc, dual arc and combined two independent-single-arcs were optimized for collimator angle 45°. VMAT treatment planning comparison was made among single-arc dual-arc and combined two independent-single-arcs. The student’s t-test (two-sided) with p ? 0.05 was applied for significant difference between dose volume indices of plans.
Results: All VMAT techniques produced clinically acceptable plans for prostate, while for head-and-neck, DA and ISAs significantly improved target coverage compared to SA. Single arc is sufficient for prostate, while inefficient in case of head-and-neck dose-planning. In spite of having different VMAT optimization approach dual arc and two combined independent-single-arcs provided very similar target coverage, while dual arc improved sparing of organs-at-risk. Similar treatment delivery times were observed for DA and ISAs VMAT techniques.
Conclusion: Single arc is sufficient for prostate, while inefficient in case of head-and-neck dose-planning.Dual arc and two combined independent-single-arcs provided similar PTV coverage, while DA provided better sparing of organs at risk. Continuous...
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| first_indexed | 2024-03-13T09:43:02Z |
| format | Article |
| id | doaj.art-f8e49c2a609d447992876a8a23844148 |
| institution | Directory Open Access Journal |
| issn | 0030-9982 |
| language | English |
| last_indexed | 2024-03-13T09:43:02Z |
| publishDate | 2021-11-01 |
| publisher | Pakistan Medical Association |
| record_format | Article |
| series | Journal of the Pakistan Medical Association |
| spelling | doaj.art-f8e49c2a609d447992876a8a238441482023-05-25T04:24:04ZengPakistan Medical AssociationJournal of the Pakistan Medical Association0030-99822021-11-0171410.47391/JPMA.710Optimisation of user-selectable volumetric modulated arc therapy (VMAT) planning parameters: A study of VMAT arcs for prostate and head-and-neck cancersGhulam Murtaza 0Zaheer Abbas Gillani1Shahid Mehmood2Jalil Ur Rehman3Ehsan Ullah Khan4Department of Medical Imaging , School of Health Sciences, University of Management and Technology, Lahore, PakistanDepartment of Physics, Baluchistan University of Information Technology, Engineering and Management Sciences, Quetta, PakistanDepartment of Oncology, Combined Military Hospital, Rawalpindi, PakistanDepartment of Physics, Baluchistan University of Information Technology, Engineering and Management Sciences, Quetta, PakistanDepartment of Physics, University of Sialkot, Sialkot, Pakistan Objective: To evaluate different VMAT planning techniques for a multi-leaf collimator (MLC)providing maximum aperture of 21 × 16 cm². Methods: A VMAT planning study of nine prostate and nine head-and-neck cancer patients was carried out. The patients were previously treated with Intensity Modulated Radiotherapy (IMRT) technique during 2014-15, at radiation oncology SanBortolo Hospital, Vicenza, Italy. Three VMAT plans for each of prostate and head-and-neck cancer patient were optimized using Pinnacle treatment planning system for 6MV photon beam from ElektaSynergyS®Linac system. Single arc, dual arc and combined two independent-single-arcs were optimized for collimator angle 45°. VMAT treatment planning comparison was made among single-arc dual-arc and combined two independent-single-arcs. The student’s t-test (two-sided) with p ? 0.05 was applied for significant difference between dose volume indices of plans. Results: All VMAT techniques produced clinically acceptable plans for prostate, while for head-and-neck, DA and ISAs significantly improved target coverage compared to SA. Single arc is sufficient for prostate, while inefficient in case of head-and-neck dose-planning. In spite of having different VMAT optimization approach dual arc and two combined independent-single-arcs provided very similar target coverage, while dual arc improved sparing of organs-at-risk. Similar treatment delivery times were observed for DA and ISAs VMAT techniques. Conclusion: Single arc is sufficient for prostate, while inefficient in case of head-and-neck dose-planning.Dual arc and two combined independent-single-arcs provided similar PTV coverage, while DA provided better sparing of organs at risk. Continuous... https://www.ojs.jpma.org.pk/index.php/public_html/article/view/532 |
| spellingShingle | Ghulam Murtaza Zaheer Abbas Gillani Shahid Mehmood Jalil Ur Rehman Ehsan Ullah Khan Optimisation of user-selectable volumetric modulated arc therapy (VMAT) planning parameters: A study of VMAT arcs for prostate and head-and-neck cancers Journal of the Pakistan Medical Association |
| title | Optimisation of user-selectable volumetric modulated arc therapy (VMAT) planning parameters: A study of VMAT arcs for prostate and head-and-neck cancers |
| title_full | Optimisation of user-selectable volumetric modulated arc therapy (VMAT) planning parameters: A study of VMAT arcs for prostate and head-and-neck cancers |
| title_fullStr | Optimisation of user-selectable volumetric modulated arc therapy (VMAT) planning parameters: A study of VMAT arcs for prostate and head-and-neck cancers |
| title_full_unstemmed | Optimisation of user-selectable volumetric modulated arc therapy (VMAT) planning parameters: A study of VMAT arcs for prostate and head-and-neck cancers |
| title_short | Optimisation of user-selectable volumetric modulated arc therapy (VMAT) planning parameters: A study of VMAT arcs for prostate and head-and-neck cancers |
| title_sort | optimisation of user selectable volumetric modulated arc therapy vmat planning parameters a study of vmat arcs for prostate and head and neck cancers |
| url | https://www.ojs.jpma.org.pk/index.php/public_html/article/view/532 |
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