Cross-sectional study regarding pattern of adverse drug reactions in a tertiary care hospital, Kakinada, India

Introduction: Drugs are considered as double-edged weapons with the potential to cause benefit as well as harm. Recent studies reveal that adverse drug reactions (ADRs) imply a remarkable burden on the length of hospital stay, healthcare facilities, and sometimes they require additional investigatio...

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Main Authors: Sreenivasa Rao Bendi, Tarun Kumar Suvvari, Lakshmi Venkata Simhachalam Kutikuppala
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2021-01-01
Series:MGM Journal of Medical Sciences
Subjects:
Online Access:http://www.mgmjms.com/article.asp?issn=2347-7946;year=2021;volume=8;issue=1;spage=29;epage=32;aulast=Bendi
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author Sreenivasa Rao Bendi
Tarun Kumar Suvvari
Lakshmi Venkata Simhachalam Kutikuppala
author_facet Sreenivasa Rao Bendi
Tarun Kumar Suvvari
Lakshmi Venkata Simhachalam Kutikuppala
author_sort Sreenivasa Rao Bendi
collection DOAJ
description Introduction: Drugs are considered as double-edged weapons with the potential to cause benefit as well as harm. Recent studies reveal that adverse drug reactions (ADRs) imply a remarkable burden on the length of hospital stay, healthcare facilities, and sometimes they require additional investigations and drug therapies for the treatment of symptoms and diseases caused to the patient. So, further local studies are required to understand the scenario and to improve the safety of prescribing and monitoring drugs and improved patient adherence to medication. Objectives: To evaluate and assess the pattern of adverse drug reactions reported to the ADR Monitoring Centre, Rangaraya Medical College, Kakinada, India. Materials and Methods: The current study was a retrospective and an observational type of study carried out at the ADR Monitoring Centre of a tertiary care hospital. Total ADRs reported during the two years from June 2016 to June 2018 were included in the study. Each ADR was analyzed for demographic data, relationship to drugs as per causality assessment, and frequency of ADRs. Microsoft Excel 2019 and SPPS version 20 were used for data analysis. Results: The most common group of drugs showing ADRs were anti-retroviral therapy (ART) drugs, followed by anti-microbial agents. Most of the ADRs were probable and mild. Rash was the most frequently occurring ADR. Conclusion: The study of ADRs in a particular institute using demographic patterns will contribute to patient safety by sensitizing the clinicians in that particular institute.
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spelling doaj.art-f8e91a50b4bb400eb063ba055b3ce04d2022-12-21T18:51:33ZengWolters Kluwer Medknow PublicationsMGM Journal of Medical Sciences2347-79462347-79622021-01-0181293210.4103/mgmj.mgmj_85_20Cross-sectional study regarding pattern of adverse drug reactions in a tertiary care hospital, Kakinada, IndiaSreenivasa Rao BendiTarun Kumar SuvvariLakshmi Venkata Simhachalam KutikuppalaIntroduction: Drugs are considered as double-edged weapons with the potential to cause benefit as well as harm. Recent studies reveal that adverse drug reactions (ADRs) imply a remarkable burden on the length of hospital stay, healthcare facilities, and sometimes they require additional investigations and drug therapies for the treatment of symptoms and diseases caused to the patient. So, further local studies are required to understand the scenario and to improve the safety of prescribing and monitoring drugs and improved patient adherence to medication. Objectives: To evaluate and assess the pattern of adverse drug reactions reported to the ADR Monitoring Centre, Rangaraya Medical College, Kakinada, India. Materials and Methods: The current study was a retrospective and an observational type of study carried out at the ADR Monitoring Centre of a tertiary care hospital. Total ADRs reported during the two years from June 2016 to June 2018 were included in the study. Each ADR was analyzed for demographic data, relationship to drugs as per causality assessment, and frequency of ADRs. Microsoft Excel 2019 and SPPS version 20 were used for data analysis. Results: The most common group of drugs showing ADRs were anti-retroviral therapy (ART) drugs, followed by anti-microbial agents. Most of the ADRs were probable and mild. Rash was the most frequently occurring ADR. Conclusion: The study of ADRs in a particular institute using demographic patterns will contribute to patient safety by sensitizing the clinicians in that particular institute.http://www.mgmjms.com/article.asp?issn=2347-7946;year=2021;volume=8;issue=1;spage=29;epage=32;aulast=Bendiadverse drug reactionanti-microbial drugsanti-retroviral therapy
spellingShingle Sreenivasa Rao Bendi
Tarun Kumar Suvvari
Lakshmi Venkata Simhachalam Kutikuppala
Cross-sectional study regarding pattern of adverse drug reactions in a tertiary care hospital, Kakinada, India
MGM Journal of Medical Sciences
adverse drug reaction
anti-microbial drugs
anti-retroviral therapy
title Cross-sectional study regarding pattern of adverse drug reactions in a tertiary care hospital, Kakinada, India
title_full Cross-sectional study regarding pattern of adverse drug reactions in a tertiary care hospital, Kakinada, India
title_fullStr Cross-sectional study regarding pattern of adverse drug reactions in a tertiary care hospital, Kakinada, India
title_full_unstemmed Cross-sectional study regarding pattern of adverse drug reactions in a tertiary care hospital, Kakinada, India
title_short Cross-sectional study regarding pattern of adverse drug reactions in a tertiary care hospital, Kakinada, India
title_sort cross sectional study regarding pattern of adverse drug reactions in a tertiary care hospital kakinada india
topic adverse drug reaction
anti-microbial drugs
anti-retroviral therapy
url http://www.mgmjms.com/article.asp?issn=2347-7946;year=2021;volume=8;issue=1;spage=29;epage=32;aulast=Bendi
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