The Psychedelic Debriefing in Alcohol Dependence Treatment: Illustrating Key Change Phenomena through Qualitative Content Analysis of Clinical Sessions

Research on the clinical applications of psychedelic-assisted psychotherapy has demonstrated promising early results for treatment of alcohol dependence. Detailed description of the content and methods of psychedelic-assisted psychotherapy, as it is conducted in clinical settings, is scarce.Methods:...

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Main Authors: Elizabeth M. Nielson, Darrick G. May, Alyssa A. Forcehimes, Michael P. Bogenschutz
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-02-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2018.00132/full
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author Elizabeth M. Nielson
Darrick G. May
Alyssa A. Forcehimes
Michael P. Bogenschutz
author_facet Elizabeth M. Nielson
Darrick G. May
Alyssa A. Forcehimes
Michael P. Bogenschutz
author_sort Elizabeth M. Nielson
collection DOAJ
description Research on the clinical applications of psychedelic-assisted psychotherapy has demonstrated promising early results for treatment of alcohol dependence. Detailed description of the content and methods of psychedelic-assisted psychotherapy, as it is conducted in clinical settings, is scarce.Methods: An open-label pilot (proof-of-concept) study of psilocybin-assisted treatment of alcohol dependence (NCT01534494) was conducted to generate data for a phase 2 RCT (NCT02061293) of a similar treatment in a larger population. The present paper presents a qualitative content analysis of the 17 debriefing sessions conducted in the pilot study, which occurred the day after corresponding psilocybin medication sessions.Results: Participants articulated a series of key phenomena related to change in drinking outcomes and acute subjective effects of psilocybin.Discussion: The data illuminate change processes in patients' own words during clinical sessions, shedding light on potential therapeutic mechanisms of change and how participants express effects of psilocybin. This study is unique in analyzing actual clinical sessions, as opposed to interviews of patients conducted separately from treatment.
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spelling doaj.art-f8ec58ac1d994748a77322530cec88062022-12-21T18:14:57ZengFrontiers Media S.A.Frontiers in Pharmacology1663-98122018-02-01910.3389/fphar.2018.00132325053The Psychedelic Debriefing in Alcohol Dependence Treatment: Illustrating Key Change Phenomena through Qualitative Content Analysis of Clinical SessionsElizabeth M. Nielson0Darrick G. May1Alyssa A. Forcehimes2Michael P. Bogenschutz3Department of Psychiatry, NYU School of Medicine, New York University, New York, NY, United StatesDepartment of Psychiatry & Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, United StatesTrain for Change, Inc., Phoenix, AZ, United StatesDepartment of Psychiatry, NYU School of Medicine, New York University, New York, NY, United StatesResearch on the clinical applications of psychedelic-assisted psychotherapy has demonstrated promising early results for treatment of alcohol dependence. Detailed description of the content and methods of psychedelic-assisted psychotherapy, as it is conducted in clinical settings, is scarce.Methods: An open-label pilot (proof-of-concept) study of psilocybin-assisted treatment of alcohol dependence (NCT01534494) was conducted to generate data for a phase 2 RCT (NCT02061293) of a similar treatment in a larger population. The present paper presents a qualitative content analysis of the 17 debriefing sessions conducted in the pilot study, which occurred the day after corresponding psilocybin medication sessions.Results: Participants articulated a series of key phenomena related to change in drinking outcomes and acute subjective effects of psilocybin.Discussion: The data illuminate change processes in patients' own words during clinical sessions, shedding light on potential therapeutic mechanisms of change and how participants express effects of psilocybin. This study is unique in analyzing actual clinical sessions, as opposed to interviews of patients conducted separately from treatment.http://journal.frontiersin.org/article/10.3389/fphar.2018.00132/fullalcoholismpsilocybinmotivational interviewinghallucinogenspsychedelic assisted therapyego-dissolution
spellingShingle Elizabeth M. Nielson
Darrick G. May
Alyssa A. Forcehimes
Michael P. Bogenschutz
The Psychedelic Debriefing in Alcohol Dependence Treatment: Illustrating Key Change Phenomena through Qualitative Content Analysis of Clinical Sessions
Frontiers in Pharmacology
alcoholism
psilocybin
motivational interviewing
hallucinogens
psychedelic assisted therapy
ego-dissolution
title The Psychedelic Debriefing in Alcohol Dependence Treatment: Illustrating Key Change Phenomena through Qualitative Content Analysis of Clinical Sessions
title_full The Psychedelic Debriefing in Alcohol Dependence Treatment: Illustrating Key Change Phenomena through Qualitative Content Analysis of Clinical Sessions
title_fullStr The Psychedelic Debriefing in Alcohol Dependence Treatment: Illustrating Key Change Phenomena through Qualitative Content Analysis of Clinical Sessions
title_full_unstemmed The Psychedelic Debriefing in Alcohol Dependence Treatment: Illustrating Key Change Phenomena through Qualitative Content Analysis of Clinical Sessions
title_short The Psychedelic Debriefing in Alcohol Dependence Treatment: Illustrating Key Change Phenomena through Qualitative Content Analysis of Clinical Sessions
title_sort psychedelic debriefing in alcohol dependence treatment illustrating key change phenomena through qualitative content analysis of clinical sessions
topic alcoholism
psilocybin
motivational interviewing
hallucinogens
psychedelic assisted therapy
ego-dissolution
url http://journal.frontiersin.org/article/10.3389/fphar.2018.00132/full
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