Platelet-Rich Plasma in Treatment of Temporomandibular Joint Dysfunctions: Narrative Review

Background: The aims of this narrative review were to examine up-to-date literature in order to evaluate the effectiveness of arthrocentesis or injections with platelet-rich plasma in temporomandibular affections and to compare them to arthrocentesis alone or with hyaluronic acid (HA) or to hyaluron...

Full description

Bibliographic Details
Main Authors: Francesca Zotti, Massimo Albanese, Luigi Fabrizio Rodella, Pier Francesco Nocini
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:http://www.mdpi.com/1422-0067/20/2/277
_version_ 1811317421600931840
author Francesca Zotti
Massimo Albanese
Luigi Fabrizio Rodella
Pier Francesco Nocini
author_facet Francesca Zotti
Massimo Albanese
Luigi Fabrizio Rodella
Pier Francesco Nocini
author_sort Francesca Zotti
collection DOAJ
description Background: The aims of this narrative review were to examine up-to-date literature in order to evaluate the effectiveness of arthrocentesis or injections with platelet-rich plasma in temporomandibular affections and to compare them to arthrocentesis alone or with hyaluronic acid (HA) or to hyaluronic acid injections. Methods: The search of international literature was made on the PMC, PubMed and Cochrane databases, including all full-length text of studies on humans focused on osteoarthritis and disc displacements and their treatment with platelet-rich plasma arthrocentesis or injections. All design studies were included in the review and they were examined for three different outcomes: pain, joint sound and mandibular motion. English papers were only selected. Results: Even though the low number of studies in this field, arthrocentesis with platelet-rich plasma and platelet-rich plasma injections in temporomandibular disorders’ management were found to be effective in reducing pain and joint sound as well as in improving mandibular motion in a maximum follow-up of 24 months. Conclusion: Comparison to arthrocentesis alone or to HA use in arthrocentesis or by injections provided encouraging results in terms of the effectiveness of platelet-rich plasma use.
first_indexed 2024-04-13T12:07:49Z
format Article
id doaj.art-f8f4811697f64aa7b8d06e398e7e14e9
institution Directory Open Access Journal
issn 1422-0067
language English
last_indexed 2024-04-13T12:07:49Z
publishDate 2019-01-01
publisher MDPI AG
record_format Article
series International Journal of Molecular Sciences
spelling doaj.art-f8f4811697f64aa7b8d06e398e7e14e92022-12-22T02:47:36ZengMDPI AGInternational Journal of Molecular Sciences1422-00672019-01-0120227710.3390/ijms20020277ijms20020277Platelet-Rich Plasma in Treatment of Temporomandibular Joint Dysfunctions: Narrative ReviewFrancesca Zotti0Massimo Albanese1Luigi Fabrizio Rodella2Pier Francesco Nocini3Department of Surgery, Dentistry, Paediatric and Gynaecology, University of Verona. Policlinico G. B. Rossi. Piazzale L. Scuro n.10, 37134 Verona, ItalyDepartment of Surgery, Dentistry, Paediatric and Gynaecology, University of Verona. Policlinico G. B. Rossi. Piazzale L. Scuro n.10, 37134 Verona, ItalySection of Anatomy and Pathophysiology, Department of Clinical and Experimental Sciences, University of Brescia, 25100 Brescia, ItalyDepartment of Surgery, Dentistry, Paediatric and Gynaecology, University of Verona. Policlinico G. B. Rossi. Piazzale L. Scuro n.10, 37134 Verona, ItalyBackground: The aims of this narrative review were to examine up-to-date literature in order to evaluate the effectiveness of arthrocentesis or injections with platelet-rich plasma in temporomandibular affections and to compare them to arthrocentesis alone or with hyaluronic acid (HA) or to hyaluronic acid injections. Methods: The search of international literature was made on the PMC, PubMed and Cochrane databases, including all full-length text of studies on humans focused on osteoarthritis and disc displacements and their treatment with platelet-rich plasma arthrocentesis or injections. All design studies were included in the review and they were examined for three different outcomes: pain, joint sound and mandibular motion. English papers were only selected. Results: Even though the low number of studies in this field, arthrocentesis with platelet-rich plasma and platelet-rich plasma injections in temporomandibular disorders’ management were found to be effective in reducing pain and joint sound as well as in improving mandibular motion in a maximum follow-up of 24 months. Conclusion: Comparison to arthrocentesis alone or to HA use in arthrocentesis or by injections provided encouraging results in terms of the effectiveness of platelet-rich plasma use.http://www.mdpi.com/1422-0067/20/2/277temporomandibular joint (TMJ)temporomandibular joint disorders (TMD)platelet-rich plasmaarthrocentesisinjectionhyaluronic acid
spellingShingle Francesca Zotti
Massimo Albanese
Luigi Fabrizio Rodella
Pier Francesco Nocini
Platelet-Rich Plasma in Treatment of Temporomandibular Joint Dysfunctions: Narrative Review
International Journal of Molecular Sciences
temporomandibular joint (TMJ)
temporomandibular joint disorders (TMD)
platelet-rich plasma
arthrocentesis
injection
hyaluronic acid
title Platelet-Rich Plasma in Treatment of Temporomandibular Joint Dysfunctions: Narrative Review
title_full Platelet-Rich Plasma in Treatment of Temporomandibular Joint Dysfunctions: Narrative Review
title_fullStr Platelet-Rich Plasma in Treatment of Temporomandibular Joint Dysfunctions: Narrative Review
title_full_unstemmed Platelet-Rich Plasma in Treatment of Temporomandibular Joint Dysfunctions: Narrative Review
title_short Platelet-Rich Plasma in Treatment of Temporomandibular Joint Dysfunctions: Narrative Review
title_sort platelet rich plasma in treatment of temporomandibular joint dysfunctions narrative review
topic temporomandibular joint (TMJ)
temporomandibular joint disorders (TMD)
platelet-rich plasma
arthrocentesis
injection
hyaluronic acid
url http://www.mdpi.com/1422-0067/20/2/277
work_keys_str_mv AT francescazotti plateletrichplasmaintreatmentoftemporomandibularjointdysfunctionsnarrativereview
AT massimoalbanese plateletrichplasmaintreatmentoftemporomandibularjointdysfunctionsnarrativereview
AT luigifabriziorodella plateletrichplasmaintreatmentoftemporomandibularjointdysfunctionsnarrativereview
AT pierfrancesconocini plateletrichplasmaintreatmentoftemporomandibularjointdysfunctionsnarrativereview