Elimination versus mitigation of SARS-CoV-2 in the presence of effective vaccines

Summary: There is increasing evidence that elimination strategies have resulted in better outcomes for public health, the economy, and civil liberties than have mitigation strategies throughout the first year of the COVID-19 pandemic. With vaccines that offer high protection against severe forms of...

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Main Authors: Miquel Oliu-Barton, PhD, Bary S R Pradelski, PhD, Yann Algan, ProfPhD, Michael G Baker, ProfMD, Agnes Binagwaho, ProfPhD, Gregory J Dore, ProfPhD, Ayman El-Mohandes, MD, Arnaud Fontanet, ProfPhD, Andreas Peichl, ProfPhD, Viola Priesemann, PhD, Guntram B Wolff, PhD, Gavin Yamey, ProfMD, Jeffrey V Lazarus, PhD
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:The Lancet Global Health
Online Access:http://www.sciencedirect.com/science/article/pii/S2214109X21004940
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author Miquel Oliu-Barton, PhD
Bary S R Pradelski, PhD
Yann Algan, ProfPhD
Michael G Baker, ProfMD
Agnes Binagwaho, ProfPhD
Gregory J Dore, ProfPhD
Ayman El-Mohandes, MD
Arnaud Fontanet, ProfPhD
Andreas Peichl, ProfPhD
Viola Priesemann, PhD
Guntram B Wolff, PhD
Gavin Yamey, ProfMD
Jeffrey V Lazarus, PhD
author_facet Miquel Oliu-Barton, PhD
Bary S R Pradelski, PhD
Yann Algan, ProfPhD
Michael G Baker, ProfMD
Agnes Binagwaho, ProfPhD
Gregory J Dore, ProfPhD
Ayman El-Mohandes, MD
Arnaud Fontanet, ProfPhD
Andreas Peichl, ProfPhD
Viola Priesemann, PhD
Guntram B Wolff, PhD
Gavin Yamey, ProfMD
Jeffrey V Lazarus, PhD
author_sort Miquel Oliu-Barton, PhD
collection DOAJ
description Summary: There is increasing evidence that elimination strategies have resulted in better outcomes for public health, the economy, and civil liberties than have mitigation strategies throughout the first year of the COVID-19 pandemic. With vaccines that offer high protection against severe forms of COVID-19, and increasing vaccination coverage, policy makers have had to reassess the trade-offs between different options. The desirability and feasibility of eliminating SARS-CoV-2 compared with other strategies should also be re-evaluated from the perspective of different fields, including epidemiology, public health, and economics. To end the pandemic as soon as possible—be it through elimination or reaching an acceptable endemic level—several key topics have emerged centring around coordination, both locally and internationally, and vaccine distribution. Without coordination it is difficult if not impossible to sustain elimination, which is particularly relevant in highly connected regions, such as Europe. Regarding vaccination, concerns remain with respect to equitable distribution, and the risk of the emergence of new variants of concern. Looking forward, it is crucial to overcome the dichotomy between elimination and mitigation, and to jointly define a long-term objective that can accommodate different political and societal realities.
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spelling doaj.art-f8fc892828924ce795cd0901f5397ff92022-12-21T18:12:00ZengElsevierThe Lancet Global Health2214-109X2022-01-01101e142e147Elimination versus mitigation of SARS-CoV-2 in the presence of effective vaccinesMiquel Oliu-Barton, PhD0Bary S R Pradelski, PhD1Yann Algan, ProfPhD2Michael G Baker, ProfMD3Agnes Binagwaho, ProfPhD4Gregory J Dore, ProfPhD5Ayman El-Mohandes, MD6Arnaud Fontanet, ProfPhD7Andreas Peichl, ProfPhD8Viola Priesemann, PhD9Guntram B Wolff, PhD10Gavin Yamey, ProfMD11Jeffrey V Lazarus, PhD12Université Paris-Dauphine–PSL, Paris, France; Bruegel, Brussels, Belgium; Esade Centre for Economic Policy, Madrid, Spain; Correspondence to: Dr Miquel Oliu-Barton, Université Paris-Dauphine–PSL, 75016 Paris, FranceFrench National Centre for Scientific Research, Grenoble, France; Oxford-Man Institute of Quantitative Finance, University of Oxford, Oxford, UKHEC Paris, Jouy-en-Josas, France; Council of Economic Analysis, Paris, FranceUniversity of Otago, Wellington, New ZealandUniversity of Global Health Equity, Kigali, RwandaKirby Institute, University of New South Wales, Sydney, NSW, AustraliaCity University of New York, New York, NY, USAEmerging Diseases Epidemiology Unit, Institut Pasteur, Université de Paris, Paris, France; Conservatoire National des Arts et Métiers, PACRI Unit, Paris, FranceUniversity of Munich, Munich, Germany; ifo Institute, Munich, Germany; CESifo, Munich, GermanyMax Planck Institute for Dynamics and Self-Organization, Göttingen, GermanyBruegel, Brussels, BelgiumCentre for Policy Impact in Global Health, Duke Global Health Institute, Duke University, Durham, NC, USABarcelona Institute for Global Health (ISGlobal), Hospital Clínic, University of Barcelona, Barcelona, SpainSummary: There is increasing evidence that elimination strategies have resulted in better outcomes for public health, the economy, and civil liberties than have mitigation strategies throughout the first year of the COVID-19 pandemic. With vaccines that offer high protection against severe forms of COVID-19, and increasing vaccination coverage, policy makers have had to reassess the trade-offs between different options. The desirability and feasibility of eliminating SARS-CoV-2 compared with other strategies should also be re-evaluated from the perspective of different fields, including epidemiology, public health, and economics. To end the pandemic as soon as possible—be it through elimination or reaching an acceptable endemic level—several key topics have emerged centring around coordination, both locally and internationally, and vaccine distribution. Without coordination it is difficult if not impossible to sustain elimination, which is particularly relevant in highly connected regions, such as Europe. Regarding vaccination, concerns remain with respect to equitable distribution, and the risk of the emergence of new variants of concern. Looking forward, it is crucial to overcome the dichotomy between elimination and mitigation, and to jointly define a long-term objective that can accommodate different political and societal realities.http://www.sciencedirect.com/science/article/pii/S2214109X21004940
spellingShingle Miquel Oliu-Barton, PhD
Bary S R Pradelski, PhD
Yann Algan, ProfPhD
Michael G Baker, ProfMD
Agnes Binagwaho, ProfPhD
Gregory J Dore, ProfPhD
Ayman El-Mohandes, MD
Arnaud Fontanet, ProfPhD
Andreas Peichl, ProfPhD
Viola Priesemann, PhD
Guntram B Wolff, PhD
Gavin Yamey, ProfMD
Jeffrey V Lazarus, PhD
Elimination versus mitigation of SARS-CoV-2 in the presence of effective vaccines
The Lancet Global Health
title Elimination versus mitigation of SARS-CoV-2 in the presence of effective vaccines
title_full Elimination versus mitigation of SARS-CoV-2 in the presence of effective vaccines
title_fullStr Elimination versus mitigation of SARS-CoV-2 in the presence of effective vaccines
title_full_unstemmed Elimination versus mitigation of SARS-CoV-2 in the presence of effective vaccines
title_short Elimination versus mitigation of SARS-CoV-2 in the presence of effective vaccines
title_sort elimination versus mitigation of sars cov 2 in the presence of effective vaccines
url http://www.sciencedirect.com/science/article/pii/S2214109X21004940
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