Application of a deep generative model produces novel and diverse functional peptides against microbial resistance

Application of a deep generative model produces novel and diverse functional peptides against microbial resistance

Antimicrobial resistance could threaten millions of lives in the immediate future. Antimicrobial peptides (AMPs) are an alternative to conventional antibiotics practice against infectious diseases. Despite the potential contribution of AMPs to the antibiotic’s world, their development and optimizati...

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Bibliographic Details
Main Authors: Jiashun Mao, Shenghui Guan, Yongqing Chen, Amir Zeb, Qingxiang Sun, Ranlan Lu, Jie Dong, Jianmin Wang, Dongsheng Cao
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
AMPs
Deep generative model
Antimicrobial resistance
Transformer
LSTM
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037022005864

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