Hepatopulmonary Syndrome: A Brief Review
Hepatopulmonary syndrome (HPS) is a pulmonary complication of liver disease characterized by arterial hypoxemia. Mechanisms related to this event are diffusion-perfusion flaw, ventilation-perfusion (V/Q) mismatch, and direct arteriovenous shunts. Diagnosis of HPS is based on the presence of liver di...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Sciendo
2016-06-01
|
| Series: | Romanian Journal of Internal Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1515/rjim-2016-0015 |
| _version_ | 1828399272475754496 |
|---|---|
| author | Amin Zulkifli Amin Hilman Zulkifli Tedyanto Nadim Marchian |
| author_facet | Amin Zulkifli Amin Hilman Zulkifli Tedyanto Nadim Marchian |
| author_sort | Amin Zulkifli |
| collection | DOAJ |
| description | Hepatopulmonary syndrome (HPS) is a pulmonary complication of liver disease characterized by arterial hypoxemia. Mechanisms related to this event are diffusion-perfusion flaw, ventilation-perfusion (V/Q) mismatch, and direct arteriovenous shunts. Diagnosis of HPS is based on the presence of liver disease or portal hypertension, increased alveolar-arterial (A-a) PO2, and intrapulmonary vascular dilatations (IPVD). Lung transplantation (LT) remains the most effective therapy for HPS. In spite of its poor prognosis, we could improve the quality of life and survival rate of patients. |
| first_indexed | 2024-12-10T09:15:02Z |
| format | Article |
| id | doaj.art-f904e5d04891498a93c5e34f930ed175 |
| institution | Directory Open Access Journal |
| issn | 2501-062X |
| language | English |
| last_indexed | 2024-12-10T09:15:02Z |
| publishDate | 2016-06-01 |
| publisher | Sciendo |
| record_format | Article |
| series | Romanian Journal of Internal Medicine |
| spelling | doaj.art-f904e5d04891498a93c5e34f930ed1752022-12-22T01:54:54ZengSciendoRomanian Journal of Internal Medicine2501-062X2016-06-01542939710.1515/rjim-2016-0015rjim-2016-0015Hepatopulmonary Syndrome: A Brief ReviewAmin Zulkifli0Amin Hilman Zulkifli1Tedyanto Nadim Marchian2Division of Respirology and Critical Care, Department of Internal Medicine, Faculty of Medicine, University of Indonesia, Jakarta, IndonesiaDepartment of Internal Medicine, Faculty of Medicine, University of Indonesia, Jakarta, IndonesiaFaculty of Medicine, University of Indonesia, Jakarta, IndonesiaHepatopulmonary syndrome (HPS) is a pulmonary complication of liver disease characterized by arterial hypoxemia. Mechanisms related to this event are diffusion-perfusion flaw, ventilation-perfusion (V/Q) mismatch, and direct arteriovenous shunts. Diagnosis of HPS is based on the presence of liver disease or portal hypertension, increased alveolar-arterial (A-a) PO2, and intrapulmonary vascular dilatations (IPVD). Lung transplantation (LT) remains the most effective therapy for HPS. In spite of its poor prognosis, we could improve the quality of life and survival rate of patients.https://doi.org/10.1515/rjim-2016-0015hepatopulmonary syndromeliver cirrhosisliver diseaselung diseaseportal hypertension |
| spellingShingle | Amin Zulkifli Amin Hilman Zulkifli Tedyanto Nadim Marchian Hepatopulmonary Syndrome: A Brief Review Romanian Journal of Internal Medicine hepatopulmonary syndrome liver cirrhosis liver disease lung disease portal hypertension |
| title | Hepatopulmonary Syndrome: A Brief Review |
| title_full | Hepatopulmonary Syndrome: A Brief Review |
| title_fullStr | Hepatopulmonary Syndrome: A Brief Review |
| title_full_unstemmed | Hepatopulmonary Syndrome: A Brief Review |
| title_short | Hepatopulmonary Syndrome: A Brief Review |
| title_sort | hepatopulmonary syndrome a brief review |
| topic | hepatopulmonary syndrome liver cirrhosis liver disease lung disease portal hypertension |
| url | https://doi.org/10.1515/rjim-2016-0015 |
| work_keys_str_mv | AT aminzulkifli hepatopulmonarysyndromeabriefreview AT aminhilmanzulkifli hepatopulmonarysyndromeabriefreview AT tedyantonadimmarchian hepatopulmonarysyndromeabriefreview |