An unusual case of Takayasu arteritis presenting with persistent cough in a young female patient: A case report

Takayasu arteritis (TA) is a chronic granulomatous inflammatory arteritis of large vessels. Females aged 20-40 are usually affected and the manifestations can range from asymptomatic disease to major cardiovascular and neurological abnormalities. Herein, we present a case of a 20-year-old female who...

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Bibliographic Details
Main Authors: Yara Ameerah, MD, Serin Moghrabi, MD, Ahmed Awadghanem, MD, Rifat Hanbali, MD, Mosab Maree, MD
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:Radiology Case Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S1930043323008336
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Summary:Takayasu arteritis (TA) is a chronic granulomatous inflammatory arteritis of large vessels. Females aged 20-40 are usually affected and the manifestations can range from asymptomatic disease to major cardiovascular and neurological abnormalities. Herein, we present a case of a 20-year-old female who had a persistent cough as the initial manifestation of an underlying TA. She had a free past medical history. The patient sought medical help multiple times and took many antibiotics with no improvement. Laboratory tests showed a marked elevation in inflammatory markers so the patient was admitted for further investigations. CT scan showed a circumferential mural thickening involving mainly the descending thoracic aorta which is highly suggestive of an underlying chronic granulomatous vasculitis behind this. Our patient was treated with a combination of corticosteroid and azathioprine and showed substantial improvement after 2 weeks. TA can present with various symptoms. Therefore, patients presenting with atypical symptoms and late-onset vascular symptoms need a high degree of suspicion with close follow-up to allow early detection of any complication.
ISSN:1930-0433