An unusual case of Takayasu arteritis presenting with persistent cough in a young female patient: A case report
Takayasu arteritis (TA) is a chronic granulomatous inflammatory arteritis of large vessels. Females aged 20-40 are usually affected and the manifestations can range from asymptomatic disease to major cardiovascular and neurological abnormalities. Herein, we present a case of a 20-year-old female who...
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| Format: | Article |
| Language: | English |
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Elsevier
2024-02-01
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| Series: | Radiology Case Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1930043323008336 |
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| author | Yara Ameerah, MD Serin Moghrabi, MD Ahmed Awadghanem, MD Rifat Hanbali, MD Mosab Maree, MD |
| author_facet | Yara Ameerah, MD Serin Moghrabi, MD Ahmed Awadghanem, MD Rifat Hanbali, MD Mosab Maree, MD |
| author_sort | Yara Ameerah, MD |
| collection | DOAJ |
| description | Takayasu arteritis (TA) is a chronic granulomatous inflammatory arteritis of large vessels. Females aged 20-40 are usually affected and the manifestations can range from asymptomatic disease to major cardiovascular and neurological abnormalities. Herein, we present a case of a 20-year-old female who had a persistent cough as the initial manifestation of an underlying TA. She had a free past medical history. The patient sought medical help multiple times and took many antibiotics with no improvement. Laboratory tests showed a marked elevation in inflammatory markers so the patient was admitted for further investigations. CT scan showed a circumferential mural thickening involving mainly the descending thoracic aorta which is highly suggestive of an underlying chronic granulomatous vasculitis behind this. Our patient was treated with a combination of corticosteroid and azathioprine and showed substantial improvement after 2 weeks. TA can present with various symptoms. Therefore, patients presenting with atypical symptoms and late-onset vascular symptoms need a high degree of suspicion with close follow-up to allow early detection of any complication. |
| first_indexed | 2024-03-09T01:29:53Z |
| format | Article |
| id | doaj.art-f906ce93e4744e548115fd14b8757ce5 |
| institution | Directory Open Access Journal |
| issn | 1930-0433 |
| language | English |
| last_indexed | 2024-03-09T01:29:53Z |
| publishDate | 2024-02-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Radiology Case Reports |
| spelling | doaj.art-f906ce93e4744e548115fd14b8757ce52023-12-10T06:14:35ZengElsevierRadiology Case Reports1930-04332024-02-01192651653An unusual case of Takayasu arteritis presenting with persistent cough in a young female patient: A case reportYara Ameerah, MD0Serin Moghrabi, MD1Ahmed Awadghanem, MD2Rifat Hanbali, MD3Mosab Maree, MD4Department of Medicine, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, PalestineDepartment of Medicine, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, PalestineDepartment of Medicine, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine; Department of Radiology, An-Najah National University Hospital, Nablus, PalestineDepartment of Rheumatology, An-Najah National Hospital, Nablus, PalestineDepartment of Medicine, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine; Department of Radiology, An-Najah National University Hospital, Nablus, Palestine; Corresponding author.Takayasu arteritis (TA) is a chronic granulomatous inflammatory arteritis of large vessels. Females aged 20-40 are usually affected and the manifestations can range from asymptomatic disease to major cardiovascular and neurological abnormalities. Herein, we present a case of a 20-year-old female who had a persistent cough as the initial manifestation of an underlying TA. She had a free past medical history. The patient sought medical help multiple times and took many antibiotics with no improvement. Laboratory tests showed a marked elevation in inflammatory markers so the patient was admitted for further investigations. CT scan showed a circumferential mural thickening involving mainly the descending thoracic aorta which is highly suggestive of an underlying chronic granulomatous vasculitis behind this. Our patient was treated with a combination of corticosteroid and azathioprine and showed substantial improvement after 2 weeks. TA can present with various symptoms. Therefore, patients presenting with atypical symptoms and late-onset vascular symptoms need a high degree of suspicion with close follow-up to allow early detection of any complication.http://www.sciencedirect.com/science/article/pii/S1930043323008336Takayasu arteritisCoughAortaImmunosuppressantCase report |
| spellingShingle | Yara Ameerah, MD Serin Moghrabi, MD Ahmed Awadghanem, MD Rifat Hanbali, MD Mosab Maree, MD An unusual case of Takayasu arteritis presenting with persistent cough in a young female patient: A case report Radiology Case Reports Takayasu arteritis Cough Aorta Immunosuppressant Case report |
| title | An unusual case of Takayasu arteritis presenting with persistent cough in a young female patient: A case report |
| title_full | An unusual case of Takayasu arteritis presenting with persistent cough in a young female patient: A case report |
| title_fullStr | An unusual case of Takayasu arteritis presenting with persistent cough in a young female patient: A case report |
| title_full_unstemmed | An unusual case of Takayasu arteritis presenting with persistent cough in a young female patient: A case report |
| title_short | An unusual case of Takayasu arteritis presenting with persistent cough in a young female patient: A case report |
| title_sort | unusual case of takayasu arteritis presenting with persistent cough in a young female patient a case report |
| topic | Takayasu arteritis Cough Aorta Immunosuppressant Case report |
| url | http://www.sciencedirect.com/science/article/pii/S1930043323008336 |
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