Ultrasonic biomechanics method for vortex and wall motion of left ventricle: a phantom and in vivo study
Abstract Background The non-invasive quantitative evaluation of left ventricle (LV) function plays a critical role in clinical cardiology. This study proposes a novel ultrasonic biomechanics method by integrating both LV vortex and wall motion to fully assess and understand the LV structure and func...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2021-10-01
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| Series: | BMC Cardiovascular Disorders |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12872-021-02317-7 |
| _version_ | 1819122225127620608 |
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| author | Aohua Zhang Min Pan Long Meng Fengshu Zhang Wei Zhou Yaonan Zhang Rongqin Zheng Lili Niu Yanling Zhang |
| author_facet | Aohua Zhang Min Pan Long Meng Fengshu Zhang Wei Zhou Yaonan Zhang Rongqin Zheng Lili Niu Yanling Zhang |
| author_sort | Aohua Zhang |
| collection | DOAJ |
| description | Abstract Background The non-invasive quantitative evaluation of left ventricle (LV) function plays a critical role in clinical cardiology. This study proposes a novel ultrasonic biomechanics method by integrating both LV vortex and wall motion to fully assess and understand the LV structure and function. The purpose of this study was to validate the ultrasonic biomechanics method as a quantifiable approach to evaluate LV function. Methods Firstly, B-mode ultrasound images were acquired and processed, which were utilized to implement parameters for quantifying the LV vortex and wall motion respectively. Next, the parameters were compared in polyvinyl alcohol cryogen (PVA) phantoms with different degree of stiffness corresponding to different freezing and thawing cycles in vitro. Finally, the parameters were computed in vivo during one cardiac cycle to assess the LV function in normal and abnormal subjects in vivo. Results In vitro study, the velocity field of PVA phantom differed with stiffness (varied elasticity modulus). The peak of strain for wall motion decreases with the increase of elasticity modulus, and periodically changed values. Statistical analysis for parameters of vortex dynamics (energy dissipation index, DI; kinetic energy fluctuations, KEF; relative strength, RS; and vorticity, W) based on different elasticity (E) of phantom depicted the good viability of this algorithm. In vivo study, the results confirmed that subjects with LV dysfunction had lower vorticity and strain (S) compared to the normal group. Conclusion Ultrasonic biomechanics method can obtain the vortex and wall motion of left ventricle. The method may have potential clinical value in evaluation of LV dysfunction. |
| first_indexed | 2024-12-22T06:49:04Z |
| format | Article |
| id | doaj.art-f90844f947ec41498a207eb329baa6f3 |
| institution | Directory Open Access Journal |
| issn | 1471-2261 |
| language | English |
| last_indexed | 2024-12-22T06:49:04Z |
| publishDate | 2021-10-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Cardiovascular Disorders |
| spelling | doaj.art-f90844f947ec41498a207eb329baa6f32022-12-21T18:35:13ZengBMCBMC Cardiovascular Disorders1471-22612021-10-0121111010.1186/s12872-021-02317-7Ultrasonic biomechanics method for vortex and wall motion of left ventricle: a phantom and in vivo studyAohua Zhang0Min Pan1Long Meng2Fengshu Zhang3Wei Zhou4Yaonan Zhang5Rongqin Zheng6Lili Niu7Yanling Zhang8Department of Ultrasound, Third Affiliated Hospital, Sun Yat-Sen UniversityDepartment of Ultrasound, Shenzhen Hospital (Futian) of Guangzhou University of Chinese MedicinePaul C. Lauterbur Research Center for Biomedical Imaging, Institute of Biomedical and Health Engineering, Shenzhen Institutes of Advanced Technology, Chinese Academy of SciencesPaul C. Lauterbur Research Center for Biomedical Imaging, Institute of Biomedical and Health Engineering, Shenzhen Institutes of Advanced Technology, Chinese Academy of SciencesPaul C. Lauterbur Research Center for Biomedical Imaging, Institute of Biomedical and Health Engineering, Shenzhen Institutes of Advanced Technology, Chinese Academy of SciencesSino-Dutch Biomedical and Information Engineering School, Northeastern UniversityDepartment of Ultrasound, Third Affiliated Hospital, Sun Yat-Sen UniversityPaul C. Lauterbur Research Center for Biomedical Imaging, Institute of Biomedical and Health Engineering, Shenzhen Institutes of Advanced Technology, Chinese Academy of SciencesDepartment of Ultrasound, Third Affiliated Hospital, Sun Yat-Sen UniversityAbstract Background The non-invasive quantitative evaluation of left ventricle (LV) function plays a critical role in clinical cardiology. This study proposes a novel ultrasonic biomechanics method by integrating both LV vortex and wall motion to fully assess and understand the LV structure and function. The purpose of this study was to validate the ultrasonic biomechanics method as a quantifiable approach to evaluate LV function. Methods Firstly, B-mode ultrasound images were acquired and processed, which were utilized to implement parameters for quantifying the LV vortex and wall motion respectively. Next, the parameters were compared in polyvinyl alcohol cryogen (PVA) phantoms with different degree of stiffness corresponding to different freezing and thawing cycles in vitro. Finally, the parameters were computed in vivo during one cardiac cycle to assess the LV function in normal and abnormal subjects in vivo. Results In vitro study, the velocity field of PVA phantom differed with stiffness (varied elasticity modulus). The peak of strain for wall motion decreases with the increase of elasticity modulus, and periodically changed values. Statistical analysis for parameters of vortex dynamics (energy dissipation index, DI; kinetic energy fluctuations, KEF; relative strength, RS; and vorticity, W) based on different elasticity (E) of phantom depicted the good viability of this algorithm. In vivo study, the results confirmed that subjects with LV dysfunction had lower vorticity and strain (S) compared to the normal group. Conclusion Ultrasonic biomechanics method can obtain the vortex and wall motion of left ventricle. The method may have potential clinical value in evaluation of LV dysfunction.https://doi.org/10.1186/s12872-021-02317-7Ultrasonic imagingWall motionVortexStrainLeft ventricular dysfunction |
| spellingShingle | Aohua Zhang Min Pan Long Meng Fengshu Zhang Wei Zhou Yaonan Zhang Rongqin Zheng Lili Niu Yanling Zhang Ultrasonic biomechanics method for vortex and wall motion of left ventricle: a phantom and in vivo study BMC Cardiovascular Disorders Ultrasonic imaging Wall motion Vortex Strain Left ventricular dysfunction |
| title | Ultrasonic biomechanics method for vortex and wall motion of left ventricle: a phantom and in vivo study |
| title_full | Ultrasonic biomechanics method for vortex and wall motion of left ventricle: a phantom and in vivo study |
| title_fullStr | Ultrasonic biomechanics method for vortex and wall motion of left ventricle: a phantom and in vivo study |
| title_full_unstemmed | Ultrasonic biomechanics method for vortex and wall motion of left ventricle: a phantom and in vivo study |
| title_short | Ultrasonic biomechanics method for vortex and wall motion of left ventricle: a phantom and in vivo study |
| title_sort | ultrasonic biomechanics method for vortex and wall motion of left ventricle a phantom and in vivo study |
| topic | Ultrasonic imaging Wall motion Vortex Strain Left ventricular dysfunction |
| url | https://doi.org/10.1186/s12872-021-02317-7 |
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