Identification of penumbra in acute ischemic stroke using multimodal MR imaging analysis: A case report study
Ischemic etiology of stroke is the most common health issue. Differentiating the ischemic core from the associated penumbra is tremendously important in tailoring an effective therapeutic strategy and potential intervention. Additionally, the degree of cell damage adjacent to the ischemic core may b...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Elsevier
2020-10-01
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| Series: | Radiology Case Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1930043320303745 |
| _version_ | 1819060996204920832 |
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| author | Forough Sodaei, MSc Vahid Shahmaei, MSc |
| author_facet | Forough Sodaei, MSc Vahid Shahmaei, MSc |
| author_sort | Forough Sodaei, MSc |
| collection | DOAJ |
| description | Ischemic etiology of stroke is the most common health issue. Differentiating the ischemic core from the associated penumbra is tremendously important in tailoring an effective therapeutic strategy and potential intervention. Additionally, the degree of cell damage adjacent to the ischemic core may be either reversible or irreversible, which may also affect clinical outcomes. We describe a case of a 58-year-old female, who was diagnosed with global aphasia and fluctuating right-sided hypoesthesia. Multimodal MR imaging analysis was obtained, with cerebral blood flow and mean transit time , demonstrating an infarcted core with an even larger penumbra, suggesting potentially salvageable tissue. We concluded that quantified perfusion imaging data should be used in combination with other MR protocols to determine at-risk tissues. This case substantiates the role of multimodal imaging of the penumbra as a routine part of acute stroke workup and management. |
| first_indexed | 2024-12-21T14:35:52Z |
| format | Article |
| id | doaj.art-f90c5ccd859e459795dde1c5b3c98912 |
| institution | Directory Open Access Journal |
| issn | 1930-0433 |
| language | English |
| last_indexed | 2024-12-21T14:35:52Z |
| publishDate | 2020-10-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Radiology Case Reports |
| spelling | doaj.art-f90c5ccd859e459795dde1c5b3c989122022-12-21T19:00:20ZengElsevierRadiology Case Reports1930-04332020-10-01151020412046Identification of penumbra in acute ischemic stroke using multimodal MR imaging analysis: A case report studyForough Sodaei, MSc0Vahid Shahmaei, MSc1Department of Medical physics and Biomedical Engineering, School of Medicine, Tehran University of Medical Sciences, Tehran, IranRadiology Technology Department, School of Allied Medical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran; Corresponding author.Ischemic etiology of stroke is the most common health issue. Differentiating the ischemic core from the associated penumbra is tremendously important in tailoring an effective therapeutic strategy and potential intervention. Additionally, the degree of cell damage adjacent to the ischemic core may be either reversible or irreversible, which may also affect clinical outcomes. We describe a case of a 58-year-old female, who was diagnosed with global aphasia and fluctuating right-sided hypoesthesia. Multimodal MR imaging analysis was obtained, with cerebral blood flow and mean transit time , demonstrating an infarcted core with an even larger penumbra, suggesting potentially salvageable tissue. We concluded that quantified perfusion imaging data should be used in combination with other MR protocols to determine at-risk tissues. This case substantiates the role of multimodal imaging of the penumbra as a routine part of acute stroke workup and management.http://www.sciencedirect.com/science/article/pii/S1930043320303745Acute ischemic strokePenumbraMultimodal MR imagingPerfusion imaging |
| spellingShingle | Forough Sodaei, MSc Vahid Shahmaei, MSc Identification of penumbra in acute ischemic stroke using multimodal MR imaging analysis: A case report study Radiology Case Reports Acute ischemic stroke Penumbra Multimodal MR imaging Perfusion imaging |
| title | Identification of penumbra in acute ischemic stroke using multimodal MR imaging analysis: A case report study |
| title_full | Identification of penumbra in acute ischemic stroke using multimodal MR imaging analysis: A case report study |
| title_fullStr | Identification of penumbra in acute ischemic stroke using multimodal MR imaging analysis: A case report study |
| title_full_unstemmed | Identification of penumbra in acute ischemic stroke using multimodal MR imaging analysis: A case report study |
| title_short | Identification of penumbra in acute ischemic stroke using multimodal MR imaging analysis: A case report study |
| title_sort | identification of penumbra in acute ischemic stroke using multimodal mr imaging analysis a case report study |
| topic | Acute ischemic stroke Penumbra Multimodal MR imaging Perfusion imaging |
| url | http://www.sciencedirect.com/science/article/pii/S1930043320303745 |
| work_keys_str_mv | AT foroughsodaeimsc identificationofpenumbrainacuteischemicstrokeusingmultimodalmrimaginganalysisacasereportstudy AT vahidshahmaeimsc identificationofpenumbrainacuteischemicstrokeusingmultimodalmrimaginganalysisacasereportstudy |