Effect of sodium fluoride on myocardial damage by regulating apoptosis through JNK signaling pathway

Effect of sodium fluoride on myocardial damage by regulating apoptosis through JNK signaling pathway

BackgroundIt has been found that fluoride may cause cardiomyocyte damage. c-Jun N-terminal kinases (JNK) signaling pathway plays an important role in apoptosis, but its role in fluorosis-induced cardiomyocyte damage is still unknown yet. ObjectiveTo explore the toxic effect of sodium fluoride (NaF)...

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Bibliographic Details
Main Authors: Liting CAO, Wei XU, Baohui MA
Format: Article
Language:English
Published: Editorial Committee of Journal of Environmental and Occupational Medicine 2023-02-01
Series:环境与职业医学
Subjects:
sodium fluoride
h9c2 cardiomyocyte
jnk signaling pathway
apoptosis
oxidative stress
reactive oxygen species
Online Access:http://www.jeom.org/article/cn/10.11836/JEOM22322

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