Fluctuations in Intestinal Microbiota Following Ingestion of Natto Powder Containing <i>Bacillus subtilis var. natto</i> SONOMONO Spores: Considerations Using a Large-Scale Intestinal Microflora Database
Improving the intestinal microbiota using probiotics, prebiotics, and synbiotics has attracted attention as a method of disease prevention and treatment. This is the first study to discuss the effects of food intake on the intestinal microbiota using a large Japanese intestinal microbiota database....
| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-09-01
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| Series: | Nutrients |
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| Online Access: | https://www.mdpi.com/2072-6643/14/18/3839 |
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| author | Kanako Kono Yasufumi Murakami Aya Ebara Kana Okuma Hidetaka Tokuno Ayano Odachi Kazuya Ogasawara Emi Hidaka Teruaki Mori Kazuko Satoh Shingen Kimoto Hiroaki Masuyama Midori Takeda Shunsuke Managi |
| author_facet | Kanako Kono Yasufumi Murakami Aya Ebara Kana Okuma Hidetaka Tokuno Ayano Odachi Kazuya Ogasawara Emi Hidaka Teruaki Mori Kazuko Satoh Shingen Kimoto Hiroaki Masuyama Midori Takeda Shunsuke Managi |
| author_sort | Kanako Kono |
| collection | DOAJ |
| description | Improving the intestinal microbiota using probiotics, prebiotics, and synbiotics has attracted attention as a method of disease prevention and treatment. This is the first study to discuss the effects of food intake on the intestinal microbiota using a large Japanese intestinal microbiota database. Here, as a case study, we determined changes in the intestinal microbiota caused by ingestion of a processed natto food containing <i>B. subtilis</i><i>var. natto</i> SONOMONO spores, SONOMONO NATTO POWDER CAPSULES<sup>TM</sup>, by analyzing 16S rRNA sequence data generated using next-generation sequencing techniques. The results showed that the relative abundance of <i>Bifidobacterium</i> and <i>Blautia</i> as well as the relative abundance of <i>Bifidobacterium</i> were increased in males and females in the ingesting group, respectively. Additionally, the effects of SONOMONO NATTO POWDER CAPSULES<sup>TM</sup> intake on <i>Bifidobacterium</i> and <i>Blautia</i> abundance depended on the relative abundance of <i>Bifidobacterium</i> at baseline. Finally, analysis of a large Japanese intestinal microbiota database suggested that the bacterial genera that fluctuated with the ingestion of SONOMONO NATTO POWDER CAPSULES<sup>TM</sup> may be associated with lifestyle-related diseases such as diabetes. |
| first_indexed | 2024-03-09T22:55:44Z |
| format | Article |
| id | doaj.art-f91218a2ee27436caa4e971964b01e0d |
| institution | Directory Open Access Journal |
| issn | 2072-6643 |
| language | English |
| last_indexed | 2024-03-09T22:55:44Z |
| publishDate | 2022-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nutrients |
| spelling | doaj.art-f91218a2ee27436caa4e971964b01e0d2023-11-23T18:12:55ZengMDPI AGNutrients2072-66432022-09-011418383910.3390/nu14183839Fluctuations in Intestinal Microbiota Following Ingestion of Natto Powder Containing <i>Bacillus subtilis var. natto</i> SONOMONO Spores: Considerations Using a Large-Scale Intestinal Microflora DatabaseKanako Kono0Yasufumi Murakami1Aya Ebara2Kana Okuma3Hidetaka Tokuno4Ayano Odachi5Kazuya Ogasawara6Emi Hidaka7Teruaki Mori8Kazuko Satoh9Shingen Kimoto10Hiroaki Masuyama11Midori Takeda12Shunsuke Managi13Symbiosis Solutions Inc., Tokyo 101-0064, JapanDepartment of Biological Science and Technology, Tokyo University of Science, Tokyo 162-8601, JapanSymbiosis Solutions Inc., Tokyo 101-0064, JapanSymbiosis Solutions Inc., Tokyo 101-0064, JapanSymbiosis Solutions Inc., Tokyo 101-0064, JapanSymbiosis Solutions Inc., Tokyo 101-0064, JapanSonomono Inc., Fukuoka 810-0023, JapanSonomono Inc., Fukuoka 810-0023, JapanNational Hospital Organization Nishi-Beppu National Hospital, Oita 874-0840, JapanDepartment of Nursing, Faculty of Medicine, Oita University, Oita 879-5593, JapanKimoto and Mori Medical Holdings, Oita 875-0001, JapanSymbiosis Solutions Inc., Tokyo 101-0064, JapanUrban Institute & Department of Civil Engineering, Kyushu University, Fukuoka 819-0395, JapanUrban Institute & Department of Civil Engineering, Kyushu University, Fukuoka 819-0395, JapanImproving the intestinal microbiota using probiotics, prebiotics, and synbiotics has attracted attention as a method of disease prevention and treatment. This is the first study to discuss the effects of food intake on the intestinal microbiota using a large Japanese intestinal microbiota database. Here, as a case study, we determined changes in the intestinal microbiota caused by ingestion of a processed natto food containing <i>B. subtilis</i><i>var. natto</i> SONOMONO spores, SONOMONO NATTO POWDER CAPSULES<sup>TM</sup>, by analyzing 16S rRNA sequence data generated using next-generation sequencing techniques. The results showed that the relative abundance of <i>Bifidobacterium</i> and <i>Blautia</i> as well as the relative abundance of <i>Bifidobacterium</i> were increased in males and females in the ingesting group, respectively. Additionally, the effects of SONOMONO NATTO POWDER CAPSULES<sup>TM</sup> intake on <i>Bifidobacterium</i> and <i>Blautia</i> abundance depended on the relative abundance of <i>Bifidobacterium</i> at baseline. Finally, analysis of a large Japanese intestinal microbiota database suggested that the bacterial genera that fluctuated with the ingestion of SONOMONO NATTO POWDER CAPSULES<sup>TM</sup> may be associated with lifestyle-related diseases such as diabetes.https://www.mdpi.com/2072-6643/14/18/3839intestinal microbiotagut microbiota16S rRNA<i>Bifidobacterium</i>Blautia<i>Bacillus subtilis var. natto</i> SONOMONO |
| spellingShingle | Kanako Kono Yasufumi Murakami Aya Ebara Kana Okuma Hidetaka Tokuno Ayano Odachi Kazuya Ogasawara Emi Hidaka Teruaki Mori Kazuko Satoh Shingen Kimoto Hiroaki Masuyama Midori Takeda Shunsuke Managi Fluctuations in Intestinal Microbiota Following Ingestion of Natto Powder Containing <i>Bacillus subtilis var. natto</i> SONOMONO Spores: Considerations Using a Large-Scale Intestinal Microflora Database Nutrients intestinal microbiota gut microbiota 16S rRNA <i>Bifidobacterium</i> Blautia <i>Bacillus subtilis var. natto</i> SONOMONO |
| title | Fluctuations in Intestinal Microbiota Following Ingestion of Natto Powder Containing <i>Bacillus subtilis var. natto</i> SONOMONO Spores: Considerations Using a Large-Scale Intestinal Microflora Database |
| title_full | Fluctuations in Intestinal Microbiota Following Ingestion of Natto Powder Containing <i>Bacillus subtilis var. natto</i> SONOMONO Spores: Considerations Using a Large-Scale Intestinal Microflora Database |
| title_fullStr | Fluctuations in Intestinal Microbiota Following Ingestion of Natto Powder Containing <i>Bacillus subtilis var. natto</i> SONOMONO Spores: Considerations Using a Large-Scale Intestinal Microflora Database |
| title_full_unstemmed | Fluctuations in Intestinal Microbiota Following Ingestion of Natto Powder Containing <i>Bacillus subtilis var. natto</i> SONOMONO Spores: Considerations Using a Large-Scale Intestinal Microflora Database |
| title_short | Fluctuations in Intestinal Microbiota Following Ingestion of Natto Powder Containing <i>Bacillus subtilis var. natto</i> SONOMONO Spores: Considerations Using a Large-Scale Intestinal Microflora Database |
| title_sort | fluctuations in intestinal microbiota following ingestion of natto powder containing i bacillus subtilis var natto i sonomono spores considerations using a large scale intestinal microflora database |
| topic | intestinal microbiota gut microbiota 16S rRNA <i>Bifidobacterium</i> Blautia <i>Bacillus subtilis var. natto</i> SONOMONO |
| url | https://www.mdpi.com/2072-6643/14/18/3839 |
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