Molecular elucidation of drug-induced abnormal assemblies of the hepatitis B virus capsid protein by solid-state NMR
Hepatitis B virus (HBV) capsid assembly modulators (CAM) represent a recent class of anti-HBV antivirals. Structural approaches provide limited conformational information on the CAM-induced off-path assemblies. Here, authors use solid-state NMR to establish a structural view on assembly modulation o...
Description complète
Détails bibliographiques
| Auteurs principaux: |
Lauriane Lecoq,
Louis Brigandat,
Rebecca Huber,
Marie-Laure Fogeron,
Shishan Wang,
Marie Dujardin,
Mathilde Briday,
Thomas Wiegand,
Morgane Callon,
Alexander Malär,
David Durantel,
Dara Burdette,
Jan Martin Berke,
Beat H. Meier,
Michael Nassal,
Anja Böckmann |
|---|
| Format: | Article
|
|---|
| Langue: | English |
|---|
| Publié: |
Nature Portfolio
2023-01-01
|
|---|
| Collection: | Nature Communications
|
|---|
| Accès en ligne: | https://doi.org/10.1038/s41467-023-36219-3
|
|---|