Molecular elucidation of drug-induced abnormal assemblies of the hepatitis B virus capsid protein by solid-state NMR
Hepatitis B virus (HBV) capsid assembly modulators (CAM) represent a recent class of anti-HBV antivirals. Structural approaches provide limited conformational information on the CAM-induced off-path assemblies. Here, authors use solid-state NMR to establish a structural view on assembly modulation o...
Κύριοι συγγραφείς: | Lauriane Lecoq, Louis Brigandat, Rebecca Huber, Marie-Laure Fogeron, Shishan Wang, Marie Dujardin, Mathilde Briday, Thomas Wiegand, Morgane Callon, Alexander Malär, David Durantel, Dara Burdette, Jan Martin Berke, Beat H. Meier, Michael Nassal, Anja Böckmann |
---|---|
Μορφή: | Άρθρο |
Γλώσσα: | English |
Έκδοση: |
Nature Portfolio
2023-01-01
|
Σειρά: | Nature Communications |
Διαθέσιμο Online: | https://doi.org/10.1038/s41467-023-36219-3 |
Παρόμοια τεκμήρια
Παρόμοια τεκμήρια
-
Combining Cell-Free Protein Synthesis and NMR Into a Tool to Study Capsid Assembly Modulation
ανά: Shishan Wang, κ.ά.
Έκδοση: (2019-08-01) -
100 kHz MAS Proton-Detected NMR Spectroscopy of Hepatitis B Virus Capsids
ανά: Lauriane Lecoq, κ.ά.
Έκδοση: (2019-07-01) -
Experimental Characterization of the Hepatitis B Virus Capsid Dynamics by Solid-State NMR
ανά: Alexander A. Malär, κ.ά.
Έκδοση: (2022-01-01) -
Solid-State NMR for Studying the Structure and Dynamics of Viral Assemblies
ανά: Lauriane Lecoq, κ.ά.
Έκδοση: (2020-09-01) -
Structural conservation of HBV-like capsid proteins over hundreds of millions of years despite the shift from non-enveloped to enveloped life-style
ανά: Sara Pfister, κ.ά.
Έκδοση: (2023-03-01)