Danicamtiv Enhances Systolic Function and Frank‐Starling Behavior at Minimal Diastolic Cost in Engineered Human Myocardium

Danicamtiv Enhances Systolic Function and Frank‐Starling Behavior at Minimal Diastolic Cost in Engineered Human Myocardium

Bibliographic Details
Main Authors:	Shi Shen, Lorenzo R. Sewanan, Daniel L. Jacoby, Stuart G. Campbell
Format:	Article
Language:	English
Published:	Wiley 2021-06-01
Series:	Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:	danicamtiv engineered heart tissues inotropes myotropes omecamtiv mecarbil
Online Access:	https://www.ahajournals.org/doi/10.1161/JAHA.121.020860

Similar Items

Omecamtiv Mecarbil in the treatment of heart failure: the past, the present, and the future
by: Shujing Zhou, et al.
Published: (2024-03-01)

Omecamtiv mecarbil in precision-cut living heart failure slices: A story of a double-edged sword
by: Jorik H. Amesz, et al.
Published: (2023-09-01)

The Novel Cardiac Myosin Activator Danicamtiv Improves Cardiac Systolic Function at the Expense of Diastolic Dysfunction In Vitro and In Vivo: Implications for Clinical Applications
by: Arnold Péter Ráduly, et al.
Published: (2022-12-01)

Advanced heart failure: guideline‐directed medical therapy, diuretics, inotropes, and palliative care
by: Daniela Tomasoni, et al.
Published: (2022-06-01)

Safety and efficacy of omecamtiv mecarbil for heart failure: A systematic review and meta-analysis
by: Fadel Alqatati, et al.
Published: (2022-05-01)

Omecamtiv mecarbil augments cardiomyocyte contractile activity both at resting and systolic Ca2+ levels
by: Arnold Péter Ráduly, et al.
Published: (2023-04-01)

Altered Left Ventricular Rat Gene Expression Induced by the Myosin Activator Omecamtiv Mecarbil
by: Bachar El Oumeiri, et al.
Published: (2023-01-01)

Myofilament Alterations Associated with Human R14del-Phospholamban Cardiomyopathy
by: Mohit Kumar, et al.
Published: (2023-01-01)

Myosin with hypertrophic cardiac mutation R712L has a decreased working stroke which is rescued by omecamtiv mecarbil
by: Aaron Snoberger, et al.
Published: (2021-02-01)

Current Approaches to Worsening Heart Failure: Pathophysiological and Molecular Insights
by: Andrea D’Amato, et al.
Published: (2024-01-01)

Prognostic Benefit of New Drugs for HFrEF: A Systematic Review and Network Meta-Analysis
by: Matteo Pagnesi, et al.
Published: (2022-01-01)

Effect of the Novel Myotrope Danicamtiv on Cross‐Bridge Behavior in Human Myocardium
by: Joohee Choi, et al.
Published: (2023-10-01)

Characterization of Stimulatory Action on Voltage-Gated Na<sup>+</sup> Currents Caused by Omecamtiv Mecarbil, Known to Be a Myosin Activator
by: Chih-Yu Ting, et al.
Published: (2023-05-01)

Negative Inotropic Effect of BGP-15 on the Human Right Atrial Myocardium
by: Nóra Lampé, et al.
Published: (2020-05-01)

Advanced cardiovascular support in refractory shock
by: Ashwin Neelavar Udupa, et al.
Published: (2018-01-01)

Biliary slage as a stage of gallstone disease: the successes and difficulties of treatment
by: O. N. Minushkin, et al.
Published: (2021-01-01)

Hypertrophic cardiomyopathy: Mutations to mechanisms to therapies
by: Masataka Kawana, et al.
Published: (2022-09-01)

Erratum: Hypertrophic cardiomyopathy: Mutations to mechanisms to therapies
by: Frontiers Production Office
Published: (2022-12-01)

Identification, Localization in the Central Nervous System and Novel Myostimulatory Effect of Allatostatins in <i>Tenebrio molitor</i> Beetle
by: Jan Lubawy, et al.
Published: (2020-05-01)

Acyl ghrelin increases cardiac output while preserving right ventricular‐pulmonary arterial coupling in heart failure
by: Mikael Erhardsson, et al.
Published: (2024-02-01)

Chronic Constrictive Pericarditis in a low-income-setting: Challenges and Outcome of Surgery
by: Nwafor IA, et al.
Published: (2022-01-01)

Use of levosimendan in acute and advanced heart failure: short review on available real-world data
by: Pashkovetsky E, et al.
Published: (2019-06-01)

Role of antispasmodics in the treatment of irritable bowel syndrome
by: V. N. Drozdov, et al.
Published: (2021-05-01)

Model-based estimation of Frank-Starling curves at the patient bedside
by: Smith, R, et al.
Published: (2021)

MAGNESIUM AND MITRAL VALVE PROLAPSE. EFFICACY AND THE POINTS OF APPLICATION
by: A. G. Avtandilov, et al.
Published: (2016-01-01)

A plea for personalization of the hemodynamic management of septic shock
by: Daniel De Backer, et al.
Published: (2022-12-01)

The association of vasoactive-inotropic score and surgical patients’ outcomes: a systematic review and meta-analysis
by: Yan-ting Sun, et al.
Published: (2024-01-01)

Vasoactive-Inotropic Score as an Early Predictor of Mortality in Adult Patients with Sepsis
by: Juhyun Song, et al.
Published: (2021-01-01)

Cardiogenic shock - novelty and emerging therapeutic concepts
by: I. Petrov, et al.
Published: (2022-09-01)

Comparison of Hemodynamic Effects of Dobutamine and Ephedrine Infusions in Isoflurane-Anesthetized Horses
by: Sergio Grandisoli Garcia Filho, et al.
Published: (2023-04-01)

Cardiorespiratory and Neuroprotective Effects of Caffeine in Neonate Animal Models
by: Daniel Mota-Rojas, et al.
Published: (2023-05-01)

Anaesthetic Management for Pheochromocytoma Surgery: A Never Ending Challenge
by: Bhavya Krishna, et al.
Published: (2023-07-01)

Evidence for a lack of inotropic and chronotropic effects of glucagon and glucagon receptors in the human heart
by: Ramón Aranda-Domene, et al.
Published: (2023-05-01)

Myocardial protection with histidine-tryptophan-ketoglutarate solution in comparison with hypothermic hyperkalemic blood solution in the correction of acyanotic congenital heart diseases
by: Ahmed M. Ali, et al.
Published: (2022-09-01)

Inotropic score and vasoactive inotropic score as predictors of outcomes in congenital diaphragmatic hernia: A single center retrospective study
by: Srirupa Hari Gopal, et al.
Published: (2023-02-01)

Correlation of the vasoactive-inotropic score with the length of intensive care unit stay and COVID IgG titers, in multisystem inflammatory syndrome in children: A prospective observational study
by: Mahantesh Matti, et al.
Published: (2022-01-01)

DOBUTAMINE USAGE IN CARDIOLOGICAL PRACTICE
by: M. Yu. Giljarov
Published: (2016-01-01)

The Usage of Concomitant Beta-Blockers with Vasopressors and Inotropes in Cardiogenic Shock
by: Rachel Ryu, et al.
Published: (2022-11-01)

Improved mortality and haemodynamics with milrinone in cardiogenic shock due to acute decompensated heart failure
by: Eduard Rodenas‐Alesina, et al.
Published: (2023-08-01)

Intermittent inotropic support with levosimendan in advanced heart failure as destination therapy: The LEVO‐D registry
by: David Dobarro, et al.
Published: (2023-04-01)