Vimentin disruption by lipoxidation and electrophiles: Role of the cysteine residue and filament dynamics

Vimentin disruption by lipoxidation and electrophiles: Role of the cysteine residue and filament dynamics

The intermediate filament protein vimentin constitutes a critical sensor for electrophilic and oxidative stress, which induce extensive reorganization of the vimentin cytoskeletal network. Here, we have investigated the mechanisms underlying these effects. In vitro, electrophilic lipids, including 1...

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Bibliographic Details
Main Authors: Andreia Mónico, Sofia Duarte, María A. Pajares, Dolores Pérez-Sala
Format: Article
Language:English
Published: Elsevier 2019-05-01
Series:Redox Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231718310127

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