A Case Report of Primary Malignant Melanoma of the Gallbladder with Multiple Metastases

Primary malignant melanoma of the gallbladder is an extremely rare tumor with approximately 39 cases described in the literature so far. However, since the first case was reported in 1907, it remains controversial whether gallbladder involvement in malignant melanoma is primary or metastatic. Here,...

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Main Authors: Steven H. Adams, Erinn Luo, Daniel Lozeau, Xiaoyun Wen
Format: Article
Language:English
Published: Hindawi Limited 2023-01-01
Series:Case Reports in Pathology
Online Access:http://dx.doi.org/10.1155/2023/4847053
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author Steven H. Adams
Erinn Luo
Daniel Lozeau
Xiaoyun Wen
author_facet Steven H. Adams
Erinn Luo
Daniel Lozeau
Xiaoyun Wen
author_sort Steven H. Adams
collection DOAJ
description Primary malignant melanoma of the gallbladder is an extremely rare tumor with approximately 39 cases described in the literature so far. However, since the first case was reported in 1907, it remains controversial whether gallbladder involvement in malignant melanoma is primary or metastatic. Here, we report a case of primary malignant melanoma of the gallbladder. A 52-year-old male presented to the emergency department with right upper quadrant abdominal pain and was found to have tumefactive sludge filling the majority of the gallbladder with possible gallbladder wall thickening on ultrasonography. A laparoscopic cholecystectomy was performed for presumed acute cholecystitis. Histopathologic examination of the gallbladder revealed malignant melanoma arising from the mucosa of the gallbladder. Further clinical investigation excluded other primary sites, supporting a diagnosis of primary malignant melanoma of the gallbladder.
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spelling doaj.art-f91aab1b0c6a4e4e9fa83797d4fbed812023-12-20T05:00:02ZengHindawi LimitedCase Reports in Pathology2090-679X2023-01-01202310.1155/2023/4847053A Case Report of Primary Malignant Melanoma of the Gallbladder with Multiple MetastasesSteven H. Adams0Erinn Luo1Daniel Lozeau2Xiaoyun Wen3Stony Brook Medicine Department of PathologyWard Melville High SchoolStony Brook Medicine Department of PathologyStony Brook Medicine Department of PathologyPrimary malignant melanoma of the gallbladder is an extremely rare tumor with approximately 39 cases described in the literature so far. However, since the first case was reported in 1907, it remains controversial whether gallbladder involvement in malignant melanoma is primary or metastatic. Here, we report a case of primary malignant melanoma of the gallbladder. A 52-year-old male presented to the emergency department with right upper quadrant abdominal pain and was found to have tumefactive sludge filling the majority of the gallbladder with possible gallbladder wall thickening on ultrasonography. A laparoscopic cholecystectomy was performed for presumed acute cholecystitis. Histopathologic examination of the gallbladder revealed malignant melanoma arising from the mucosa of the gallbladder. Further clinical investigation excluded other primary sites, supporting a diagnosis of primary malignant melanoma of the gallbladder.http://dx.doi.org/10.1155/2023/4847053
spellingShingle Steven H. Adams
Erinn Luo
Daniel Lozeau
Xiaoyun Wen
A Case Report of Primary Malignant Melanoma of the Gallbladder with Multiple Metastases
Case Reports in Pathology
title A Case Report of Primary Malignant Melanoma of the Gallbladder with Multiple Metastases
title_full A Case Report of Primary Malignant Melanoma of the Gallbladder with Multiple Metastases
title_fullStr A Case Report of Primary Malignant Melanoma of the Gallbladder with Multiple Metastases
title_full_unstemmed A Case Report of Primary Malignant Melanoma of the Gallbladder with Multiple Metastases
title_short A Case Report of Primary Malignant Melanoma of the Gallbladder with Multiple Metastases
title_sort case report of primary malignant melanoma of the gallbladder with multiple metastases
url http://dx.doi.org/10.1155/2023/4847053
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