Antimicrobial photodynamic therapy in voice rehabilitation of patients after laryngectomy
The article is devoted to the problem of voice rehabilitation of patients after laryngectomy. Modern possibilities of repairing laryngeal vocal function, methods for extending the lifetime of voice prostheses are considered. The author’s method of prevention of infection of vocal prostheses using th...
Main Authors: | , , , , , |
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Format: | Article |
Language: | Russian |
Published: |
Non-profit partnership for development of domestic photodynamic therapy and photodiagnosis "Russian Photodynamic Association"
2021-04-01
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Series: | Biomedical Photonics |
Subjects: | |
Online Access: | https://www.pdt-journal.com/jour/article/view/474 |
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author | S. A. Shinkarev S. V. Boldyrev A. P. Zagadaev V. N. Podolsky V. A. Borisov Y. I. Kostyushina |
author_facet | S. A. Shinkarev S. V. Boldyrev A. P. Zagadaev V. N. Podolsky V. A. Borisov Y. I. Kostyushina |
author_sort | S. A. Shinkarev |
collection | DOAJ |
description | The article is devoted to the problem of voice rehabilitation of patients after laryngectomy. Modern possibilities of repairing laryngeal vocal function, methods for extending the lifetime of voice prostheses are considered. The author’s method of prevention of infection of vocal prostheses using the antimicrobial photodynamic therapy (PDT) with chlorin-type photosensitizer Radagel is presented. Performing antimicrobial PDT of vocal prostheses increased the average operating time to 11.9 months compared to the control group (6.8 months), where a monthly dose of 150 mg of fluconazole was used for prevention. The method developed by the authors makes it possible to significantly extend the lifetime of vocal prostheses, is devoid of adverse events, is well tolerated by patients. |
first_indexed | 2024-04-10T03:55:34Z |
format | Article |
id | doaj.art-f91be0c126824fe685f90f64398ea273 |
institution | Directory Open Access Journal |
issn | 2413-9432 |
language | Russian |
last_indexed | 2025-03-14T09:02:30Z |
publishDate | 2021-04-01 |
publisher | Non-profit partnership for development of domestic photodynamic therapy and photodiagnosis "Russian Photodynamic Association" |
record_format | Article |
series | Biomedical Photonics |
spelling | doaj.art-f91be0c126824fe685f90f64398ea2732025-03-02T12:41:34ZrusNon-profit partnership for development of domestic photodynamic therapy and photodiagnosis "Russian Photodynamic Association"Biomedical Photonics2413-94322021-04-0110110.24931/2413-9432-2021-10-1-11-16226Antimicrobial photodynamic therapy in voice rehabilitation of patients after laryngectomyS. A. Shinkarev0S. V. Boldyrev1A. P. Zagadaev2V. N. Podolsky3V. A. Borisov4Y. I. Kostyushina5Lipetsk State Oncology Clinic; Voronezh State Medical UniversityLipetsk State Oncology ClinicLipetsk State Oncology ClinicLipetsk State Oncology ClinicLipetsk State Oncology Clinic; Voronezh State Medical UniversityRyazan State Medical UniversityThe article is devoted to the problem of voice rehabilitation of patients after laryngectomy. Modern possibilities of repairing laryngeal vocal function, methods for extending the lifetime of voice prostheses are considered. The author’s method of prevention of infection of vocal prostheses using the antimicrobial photodynamic therapy (PDT) with chlorin-type photosensitizer Radagel is presented. Performing antimicrobial PDT of vocal prostheses increased the average operating time to 11.9 months compared to the control group (6.8 months), where a monthly dose of 150 mg of fluconazole was used for prevention. The method developed by the authors makes it possible to significantly extend the lifetime of vocal prostheses, is devoid of adverse events, is well tolerated by patients.https://www.pdt-journal.com/jour/article/view/474laryngeal cancerlaryngectomyvocal rehabilitationvoice prosthesisphotodynamic therapy |
spellingShingle | S. A. Shinkarev S. V. Boldyrev A. P. Zagadaev V. N. Podolsky V. A. Borisov Y. I. Kostyushina Antimicrobial photodynamic therapy in voice rehabilitation of patients after laryngectomy Biomedical Photonics laryngeal cancer laryngectomy vocal rehabilitation voice prosthesis photodynamic therapy |
title | Antimicrobial photodynamic therapy in voice rehabilitation of patients after laryngectomy |
title_full | Antimicrobial photodynamic therapy in voice rehabilitation of patients after laryngectomy |
title_fullStr | Antimicrobial photodynamic therapy in voice rehabilitation of patients after laryngectomy |
title_full_unstemmed | Antimicrobial photodynamic therapy in voice rehabilitation of patients after laryngectomy |
title_short | Antimicrobial photodynamic therapy in voice rehabilitation of patients after laryngectomy |
title_sort | antimicrobial photodynamic therapy in voice rehabilitation of patients after laryngectomy |
topic | laryngeal cancer laryngectomy vocal rehabilitation voice prosthesis photodynamic therapy |
url | https://www.pdt-journal.com/jour/article/view/474 |
work_keys_str_mv | AT sashinkarev antimicrobialphotodynamictherapyinvoicerehabilitationofpatientsafterlaryngectomy AT svboldyrev antimicrobialphotodynamictherapyinvoicerehabilitationofpatientsafterlaryngectomy AT apzagadaev antimicrobialphotodynamictherapyinvoicerehabilitationofpatientsafterlaryngectomy AT vnpodolsky antimicrobialphotodynamictherapyinvoicerehabilitationofpatientsafterlaryngectomy AT vaborisov antimicrobialphotodynamictherapyinvoicerehabilitationofpatientsafterlaryngectomy AT yikostyushina antimicrobialphotodynamictherapyinvoicerehabilitationofpatientsafterlaryngectomy |