Ceramide-1-phosphate transfer protein enhances lipid transport by disrupting hydrophobic lipid-membrane contacts.

Cellular distributions of the sphingolipid ceramide-1-phosphate (C1P) impact essential biological processes. C1P levels are spatiotemporally regulated by ceramide-1-phosphate transfer protein (CPTP), which efficiently shuttles C1P between organelle membranes. Yet, how CPTP rapidly extracts and inser...

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书目详细资料
Main Authors: Julia R Rogers, Phillip L Geissler
格式: 文件
语言:English
出版: Public Library of Science (PLoS) 2023-04-01
丛编:PLoS Computational Biology
在线阅读:https://doi.org/10.1371/journal.pcbi.1010992