Ceramide-1-phosphate transfer protein enhances lipid transport by disrupting hydrophobic lipid-membrane contacts.
Cellular distributions of the sphingolipid ceramide-1-phosphate (C1P) impact essential biological processes. C1P levels are spatiotemporally regulated by ceramide-1-phosphate transfer protein (CPTP), which efficiently shuttles C1P between organelle membranes. Yet, how CPTP rapidly extracts and inser...
Main Authors: | , |
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格式: | 文件 |
语言: | English |
出版: |
Public Library of Science (PLoS)
2023-04-01
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丛编: | PLoS Computational Biology |
在线阅读: | https://doi.org/10.1371/journal.pcbi.1010992 |