Sharpening the Molecular Scissors: Advances in Gene-Editing Technology
The ability to precisely modify human genes has been made possible by the development of tools such as meganucleases, zinc finger nucleases, TALENs, and CRISPR/Cas. These now make it possible to generate targeted deletions, insertions, gene knock outs, and point variants; to modulate gene expression...
Main Authors: | Mike Broeders, Pablo Herrero-Hernandez, Martijn P.T. Ernst, Ans T. van der Ploeg, W.W.M. Pim Pijnappel |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2020-01-01
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Series: | iScience |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2589004219305346 |
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