Reduced reward responsiveness in treatment resistant depression of middle-aged adults: Association with carotid artery stiffness and tetrahydrobiopterin

Reduced reward responsiveness in treatment resistant depression of middle-aged adults: Association with carotid artery stiffness and tetrahydrobiopterin

Nearly one third of the population diagnosed with major depressive disorder (MDD) fail to respond to two or more antidepressant drugs of adequate dose and duration. This necessitates identification of confounding psychological and physiological factors that could contribute to treatment resistant de...

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Bibliographic Details
Main Authors: Kalpana K. Barhwal, Barsha Parida, Jigyansa Pattnaik, Praveen Rowlo, Sudipta Mahakud, Suravi Patra, Bodepudi N. Rao, Bidhubhusan Mahapatra
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10470903/?tool=EBI

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