Comparison of histopathological findings of patients presenting with acute appendicitis in COVID-19 infected and non-COVID-19 infected patients.
Background: COVID-19 disease has been associated with multiple organs and causes various symptoms depending on the organ involved. Histological findings in the lungs, such as microthrombi, perivascular lymphocytic infiltrate, and necrosis/infarction, can also be seen in the histopathology of the app...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Advance Educational Institute & Research Centre
2022-06-01
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| Series: | International Journal of Endorsing Health Science Research |
| Subjects: | |
| Online Access: | https://aeirc-edu.com/ojs14/index.php/IJEHSR/article/view/778/836 |
| _version_ | 1828470863271297024 |
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| author | M. Faizan Shaikh Subhan Ahmed Sajjad Owais Ramzan Shua Nasir Lal Shehbaz Hafsa Tahir Shaikh S. Muhammad Irtiza Hashmi |
| author_facet | M. Faizan Shaikh Subhan Ahmed Sajjad Owais Ramzan Shua Nasir Lal Shehbaz Hafsa Tahir Shaikh S. Muhammad Irtiza Hashmi |
| author_sort | M. Faizan Shaikh |
| collection | DOAJ |
| description | Background: COVID-19 disease has been associated with multiple organs and causes various symptoms depending on the organ involved. Histological findings in the lungs, such as microthrombi, perivascular lymphocytic infiltrate, and necrosis/infarction, can also be seen in the histopathology of the appendix of COVID-19 +ve patients.
Methodology: This cross-sectional study was conducted in Dr. Ziauddin Hospital, a tertiary care center in Karachi, Pakistan. In this research article, the histopathology reports of the appendix of COVID-19 +ve patients presenting with acute appendicitis, either antigen or PCR positive, are compared with those of non-COVID patients who presented with acute appendicitis. The data was analyzed using SPSS 20.0, and Pearson’s Chi-Square and Cramer's V tests were performed for analysis.
Results: Comparing the histopathology reports of COVID-19 +ve and non-COVID patients presenting with acute appendicitis, an appendix of COVID-19 +ve patients shows microthrombi; perivascular lymphocytic infiltrates, and necrosis/infarction.
Conclusion: Patients who are COVID-19 +ve presenting with acute appendicitis should be treated surgically as soon as possible to reduce the risk of acute presentation, ultimately leading to perforation, and not wait for the patient to recover from COVID infection first. |
| first_indexed | 2024-12-11T05:00:54Z |
| format | Article |
| id | doaj.art-f9210b67d0e44ec6925ecce5b6a358d8 |
| institution | Directory Open Access Journal |
| issn | 2307-3748 2310-3841 |
| language | English |
| last_indexed | 2024-12-11T05:00:54Z |
| publishDate | 2022-06-01 |
| publisher | Advance Educational Institute & Research Centre |
| record_format | Article |
| series | International Journal of Endorsing Health Science Research |
| spelling | doaj.art-f9210b67d0e44ec6925ecce5b6a358d82022-12-22T01:20:09ZengAdvance Educational Institute & Research CentreInternational Journal of Endorsing Health Science Research2307-37482310-38412022-06-01102233241https://doi.org/10.29052/IJEHSR.v10.i2.2022.233-241Comparison of histopathological findings of patients presenting with acute appendicitis in COVID-19 infected and non-COVID-19 infected patients.M. Faizan Shaikh0https://orcid.org/0000-0001-9828-2648Subhan Ahmed Sajjad1https://orcid.org/0000-0002-0632-3965Owais Ramzan2https://orcid.org/0000-0002-0582-4557Shua Nasir3https://orcid.org/0000-0001-8194-9645Lal Shehbaz4https://orcid.org/0000-0003-0607-5241Hafsa Tahir Shaikh5https://orcid.org/0000-0002-8561-8437S. Muhammad Irtiza Hashmi6https://orcid.org/0000-0003-2067-5761General Surgery, Ziauddin University and Hospital, Karachi-Pakistan.General Surgery, Ziauddin University and Hospital, Karachi-Pakistan.General Surgery, Ziauddin University and Hospital, Karachi-Pakistan.Department of Emergency Medicine, Ziauddin University and Hospital, Karachi-Pakistan.Department of Emergency Medicine, Ziauddin University and Hospital, Karachi-Pakistan.Ziauddin University, Karachi-Pakistan.Ziauddin University, Karachi-Pakistan.Background: COVID-19 disease has been associated with multiple organs and causes various symptoms depending on the organ involved. Histological findings in the lungs, such as microthrombi, perivascular lymphocytic infiltrate, and necrosis/infarction, can also be seen in the histopathology of the appendix of COVID-19 +ve patients. Methodology: This cross-sectional study was conducted in Dr. Ziauddin Hospital, a tertiary care center in Karachi, Pakistan. In this research article, the histopathology reports of the appendix of COVID-19 +ve patients presenting with acute appendicitis, either antigen or PCR positive, are compared with those of non-COVID patients who presented with acute appendicitis. The data was analyzed using SPSS 20.0, and Pearson’s Chi-Square and Cramer's V tests were performed for analysis. Results: Comparing the histopathology reports of COVID-19 +ve and non-COVID patients presenting with acute appendicitis, an appendix of COVID-19 +ve patients shows microthrombi; perivascular lymphocytic infiltrates, and necrosis/infarction. Conclusion: Patients who are COVID-19 +ve presenting with acute appendicitis should be treated surgically as soon as possible to reduce the risk of acute presentation, ultimately leading to perforation, and not wait for the patient to recover from COVID infection first.https://aeirc-edu.com/ojs14/index.php/IJEHSR/article/view/778/836covid-19acute appendicitishistopathological findings |
| spellingShingle | M. Faizan Shaikh Subhan Ahmed Sajjad Owais Ramzan Shua Nasir Lal Shehbaz Hafsa Tahir Shaikh S. Muhammad Irtiza Hashmi Comparison of histopathological findings of patients presenting with acute appendicitis in COVID-19 infected and non-COVID-19 infected patients. International Journal of Endorsing Health Science Research covid-19 acute appendicitis histopathological findings |
| title | Comparison of histopathological findings of patients presenting with acute appendicitis in COVID-19 infected and non-COVID-19 infected patients. |
| title_full | Comparison of histopathological findings of patients presenting with acute appendicitis in COVID-19 infected and non-COVID-19 infected patients. |
| title_fullStr | Comparison of histopathological findings of patients presenting with acute appendicitis in COVID-19 infected and non-COVID-19 infected patients. |
| title_full_unstemmed | Comparison of histopathological findings of patients presenting with acute appendicitis in COVID-19 infected and non-COVID-19 infected patients. |
| title_short | Comparison of histopathological findings of patients presenting with acute appendicitis in COVID-19 infected and non-COVID-19 infected patients. |
| title_sort | comparison of histopathological findings of patients presenting with acute appendicitis in covid 19 infected and non covid 19 infected patients |
| topic | covid-19 acute appendicitis histopathological findings |
| url | https://aeirc-edu.com/ojs14/index.php/IJEHSR/article/view/778/836 |
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