Ganglioside GD2 Enhances the Malignant Phenotypes of Melanoma Cells by Cooperating with Integrins

Ganglioside GD2 Enhances the Malignant Phenotypes of Melanoma Cells by Cooperating with Integrins

Gangliosides have been considered to modulate cell signals in the microdomain of the cell membrane, lipid/rafts, or glycolipid-enriched microdomain/rafts (GEM/rafts). In particular, cancer-associated gangliosides were reported to enhance the malignant properties of cancer cells. In fact, GD2-positiv...

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Bibliographic Details
Main Authors: Farhana Yesmin, Robiul H. Bhuiyan, Yuhsuke Ohmi, Satoko Yamamoto, Kei Kaneko, Yuki Ohkawa, Pu Zhang, Kazunori Hamamura, Nai-Kong V. Cheung, Norihiro Kotani, Koichi Honke, Tetsuya Okajima, Mariko Kambe, Orie Tajima, Keiko Furukawa, Koichi Furukawa
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:International Journal of Molecular Sciences
Subjects:
ganglioside
cancer-associated antigen
integrin
GEM/rafts
melanoma
Online Access:https://www.mdpi.com/1422-0067/23/1/423

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