An approach to the dermatological classification of histopathological skin images using a hybridized CNN-DenseNet model

This research addresses the challenge of automating skin disease diagnosis using dermatoscopic images. The primary issue lies in accurately classifying pigmented skin lesions, which traditionally rely on manual assessment by dermatologists and are prone to subjectivity and time consumption. By integ...

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Main Authors: Anubhav De, Nilamadhab Mishra, Hsien-Tsung Chang
Format: Article
Language:English
Published: PeerJ Inc. 2024-02-01
Series:PeerJ Computer Science
Subjects:
Online Access:https://peerj.com/articles/cs-1884.pdf
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author Anubhav De
Nilamadhab Mishra
Hsien-Tsung Chang
author_facet Anubhav De
Nilamadhab Mishra
Hsien-Tsung Chang
author_sort Anubhav De
collection DOAJ
description This research addresses the challenge of automating skin disease diagnosis using dermatoscopic images. The primary issue lies in accurately classifying pigmented skin lesions, which traditionally rely on manual assessment by dermatologists and are prone to subjectivity and time consumption. By integrating a hybrid CNN-DenseNet model, this study aimed to overcome the complexities of differentiating various skin diseases and automating the diagnostic process effectively. Our methodology involved rigorous data preprocessing, exploratory data analysis, normalization, and label encoding. Techniques such as model hybridization, batch normalization and data fitting were employed to optimize the model architecture and data fitting. Initial iterations of our convolutional neural network (CNN) model achieved an accuracy of 76.22% on the test data and 75.69% on the validation data. Recognizing the need for improvement, the model was hybridized with DenseNet architecture and ResNet architecture was implemented for feature extraction and then further trained on the HAM10000 and PAD-UFES-20 datasets. Overall, our efforts resulted in a hybrid model that demonstrated an impressive accuracy of 95.7% on the HAM10000 dataset and 91.07% on the PAD-UFES-20 dataset. In comparison to recently published works, our model stands out because of its potential to effectively diagnose skin diseases such as melanocytic nevi, melanoma, benign keratosis-like lesions, basal cell carcinoma, actinic keratoses, vascular lesions, and dermatofibroma, all of which rival the diagnostic accuracy of real-world clinical specialists but also offer customization potential for more nuanced clinical uses.
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spelling doaj.art-f928462abf64422981ebd1d13e789b8f2024-02-28T15:05:28ZengPeerJ Inc.PeerJ Computer Science2376-59922024-02-0110e188410.7717/peerj-cs.1884An approach to the dermatological classification of histopathological skin images using a hybridized CNN-DenseNet modelAnubhav De0Nilamadhab Mishra1Hsien-Tsung Chang2School of Computing Science & Engineering, VIT Bhopal University, Madhya Pradesh, IndiaSchool of Computing Science & Engineering, VIT Bhopal University, Madhya Pradesh, IndiaDepartment of Computer Science and Information Engineering, Chang Gung University, Taoyuan, TaiwanThis research addresses the challenge of automating skin disease diagnosis using dermatoscopic images. The primary issue lies in accurately classifying pigmented skin lesions, which traditionally rely on manual assessment by dermatologists and are prone to subjectivity and time consumption. By integrating a hybrid CNN-DenseNet model, this study aimed to overcome the complexities of differentiating various skin diseases and automating the diagnostic process effectively. Our methodology involved rigorous data preprocessing, exploratory data analysis, normalization, and label encoding. Techniques such as model hybridization, batch normalization and data fitting were employed to optimize the model architecture and data fitting. Initial iterations of our convolutional neural network (CNN) model achieved an accuracy of 76.22% on the test data and 75.69% on the validation data. Recognizing the need for improvement, the model was hybridized with DenseNet architecture and ResNet architecture was implemented for feature extraction and then further trained on the HAM10000 and PAD-UFES-20 datasets. Overall, our efforts resulted in a hybrid model that demonstrated an impressive accuracy of 95.7% on the HAM10000 dataset and 91.07% on the PAD-UFES-20 dataset. In comparison to recently published works, our model stands out because of its potential to effectively diagnose skin diseases such as melanocytic nevi, melanoma, benign keratosis-like lesions, basal cell carcinoma, actinic keratoses, vascular lesions, and dermatofibroma, all of which rival the diagnostic accuracy of real-world clinical specialists but also offer customization potential for more nuanced clinical uses.https://peerj.com/articles/cs-1884.pdfConvolutional neural networksHybridized densenet modelMulticlass classificationConfocal microscopy analysisSkin histopathological image analysisSkin disease classification
spellingShingle Anubhav De
Nilamadhab Mishra
Hsien-Tsung Chang
An approach to the dermatological classification of histopathological skin images using a hybridized CNN-DenseNet model
PeerJ Computer Science
Convolutional neural networks
Hybridized densenet model
Multiclass classification
Confocal microscopy analysis
Skin histopathological image analysis
Skin disease classification
title An approach to the dermatological classification of histopathological skin images using a hybridized CNN-DenseNet model
title_full An approach to the dermatological classification of histopathological skin images using a hybridized CNN-DenseNet model
title_fullStr An approach to the dermatological classification of histopathological skin images using a hybridized CNN-DenseNet model
title_full_unstemmed An approach to the dermatological classification of histopathological skin images using a hybridized CNN-DenseNet model
title_short An approach to the dermatological classification of histopathological skin images using a hybridized CNN-DenseNet model
title_sort approach to the dermatological classification of histopathological skin images using a hybridized cnn densenet model
topic Convolutional neural networks
Hybridized densenet model
Multiclass classification
Confocal microscopy analysis
Skin histopathological image analysis
Skin disease classification
url https://peerj.com/articles/cs-1884.pdf
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