Dose-Dependent Protective Effect of Bisperoxovanadium against Acute Cerebral Ischemia in a Rat Model of Ischemia/Reperfusion Injury

Dose-Dependent Protective Effect of Bisperoxovanadium against Acute Cerebral Ischemia in a Rat Model of Ischemia/Reperfusion Injury

PTEN (phosphatase and tensin homologue deleted on chromosome 10) is a dual-specificity lipid and protein phosphatase. The loss of PTEN was originally discovered in numerous human cancers. PTEN inhibition by bisperoxovanadium (bpV) reduces neurological damage after ischemic brain injury. The purpose...

Full description

Bibliographic Details
Main Authors: Heng-Li Tian, Shi-Wen Chen, Hao Chen, Fang Yuan, Jun Ding, Jian-Yi Guo
Format: Article
Language:English
Published: MDPI AG 2013-06-01
Series:International Journal of Molecular Sciences
Subjects:
bisperoxovanadium
phosphatase and tensin homologue deleted on chromosome 10
cerebral ischemia
neuroprotection
Akt
Online Access:http://www.mdpi.com/1422-0067/14/6/12013

Internet

http://www.mdpi.com/1422-0067/14/6/12013

Similar Items