Dose-Dependent Protective Effect of Bisperoxovanadium against Acute Cerebral Ischemia in a Rat Model of Ischemia/Reperfusion Injury

Dose-Dependent Protective Effect of Bisperoxovanadium against Acute Cerebral Ischemia in a Rat Model of Ischemia/Reperfusion Injury

PTEN (phosphatase and tensin homologue deleted on chromosome 10) is a dual-specificity lipid and protein phosphatase. The loss of PTEN was originally discovered in numerous human cancers. PTEN inhibition by bisperoxovanadium (bpV) reduces neurological damage after ischemic brain injury. The purpose...

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Bibliographic Details
Main Authors:	Heng-Li Tian, Shi-Wen Chen, Hao Chen, Fang Yuan, Jun Ding, Jian-Yi Guo
Format:	Article
Language:	English
Published:	MDPI AG 2013-06-01
Series:	International Journal of Molecular Sciences
Subjects:	bisperoxovanadium phosphatase and tensin homologue deleted on chromosome 10 cerebral ischemia neuroprotection Akt
Online Access:	http://www.mdpi.com/1422-0067/14/6/12013

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