Intranasal Vaccination Affords Localization and Persistence of Antigen-Specific CD8+ T Lymphocytes in the Female Reproductive Tract

Intranasal Vaccination Affords Localization and Persistence of Antigen-Specific CD8+ T Lymphocytes in the Female Reproductive Tract

Immunization strategies generating large numbers of antigen-specific T cells in the female reproductive tract (FRT) can provide barrier protection against sexually-transmitted pathogens, such as the human immunodeficiency virus (HIV) and human papillomaviruses (HPV). The kinetics and mechanisms of r...

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Bibliographic Details
Main Authors: Shailbala Singh, Kimberly S. Schluns, Guojun Yang, Scott M. Anthony, Michael A. Barry, K. Jagannadha Sastry
Format: Article
Language:English
Published: MDPI AG 2016-03-01
Series:Vaccines
Subjects:
Female reproductive tract
CD8+ T cells
intranasal immunization
Online Access:http://www.mdpi.com/2076-393X/4/1/7

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