Evaluation of Pre and Postoperative Polysomnographic Data in Patients with Idiopathic Parkinson’s Disease Undergoing Deep Brain Stimulation Intended Bilateral Subthalamic Nucleus
Objective:Deep brain stimulation (DBS) intended to bilateral subthalamic nucleus (STN) used in the Parkinson’s disease (PD) has been reported to lead improved subjective sleep quality, increased sleep efficiency, decreased wakefulness time after sleep, and increased total sleep time. On this basis,...
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| Format: | Article |
| Language: | English |
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Galenos Yayinevi
2019-09-01
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| Series: | Türk Uyku Tıbbı Dergisi |
| Subjects: | |
| Online Access: |
http://jtsm.org/archives/archive-detail/article-preview/evaluation-of-pre-and-postoperative-polysomnograph/30189
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| author | Nihan Altan Torun Gülçin Benbir Şenel Ayşegül Gündüz Derya Karadeniz Güneş Kızıltan Sibel Ertan Sabri Aydın Selin Yağcı Hülya Apaydın |
| author_facet | Nihan Altan Torun Gülçin Benbir Şenel Ayşegül Gündüz Derya Karadeniz Güneş Kızıltan Sibel Ertan Sabri Aydın Selin Yağcı Hülya Apaydın |
| author_sort | Nihan Altan Torun |
| collection | DOAJ |
| description | Objective:Deep brain stimulation (DBS) intended to bilateral subthalamic nucleus (STN) used in the Parkinson’s disease (PD) has been reported to lead improved subjective sleep quality, increased sleep efficiency, decreased wakefulness time after sleep, and increased total sleep time. On this basis, we aimed to evaluate the sleep structure and quality by polysomnographic (PSG) investigation parameters in patients diagnosed with idiopathic PD who were planned to undergo bilateral STN-DBS.Materials and Methods:Inclusion criteria were determined as the presence of a clinical diagnosis of idiopathic PD, being 70 years and below, having at least 5 years of disease duration, and being a suitable candidate for STN DBS surgery. Patients were excluded from the study in the presence of dementia or psychiatric disturbances, cardiac pacemaker, and history of cerebrovascular disease. Our study was approved by Local Ethical Committe of Istanbul University-Cerrahpaşa, Cerrahpaşa Faculty of Medicine, and signed consent form was obtained from participants.Results:Eight patients were included in our study; the mean age was calculated as 53.6±4.1 years. When pre- and postoperation PSG parameters were compared, the total sleep time was decreased, however it was not found statistically significant (p=0.840). REM sleep latancy was significantly shortened postoperatively (p=0.003). It was observed that other PSG parameters measuring the macro- and micro-structure of sleep did not change significantly (p>0.050).Conclusion:Many studies have reported substantial improvements in parameters obtained by polysomnography, while only one study has reported that sleep was not normalized although subjective sleep quality was increased. In our study, except for shortening in the REM sleep period, no significant improvement in PSG parameters was observed. The effect of bilateral STB-DBS on sleep is still one of the controversial issues and waits to be demonstrated in the larger series. |
| first_indexed | 2024-04-10T10:11:56Z |
| format | Article |
| id | doaj.art-f935fb2190dc4e4dab0eb0c3c868c1fb |
| institution | Directory Open Access Journal |
| issn | 2148-1504 2148-1504 |
| language | English |
| last_indexed | 2024-04-10T10:11:56Z |
| publishDate | 2019-09-01 |
| publisher | Galenos Yayinevi |
| record_format | Article |
| series | Türk Uyku Tıbbı Dergisi |
| spelling | doaj.art-f935fb2190dc4e4dab0eb0c3c868c1fb2023-02-15T16:22:08ZengGalenos YayineviTürk Uyku Tıbbı Dergisi2148-15042148-15042019-09-0163535810.4274/jtsm.galenos.2019.0071913049054Evaluation of Pre and Postoperative Polysomnographic Data in Patients with Idiopathic Parkinson’s Disease Undergoing Deep Brain Stimulation Intended Bilateral Subthalamic NucleusNihan Altan Torun0Gülçin Benbir Şenel1Ayşegül Gündüz2Derya Karadeniz3Güneş Kızıltan4Sibel Ertan5Sabri Aydın6Selin Yağcı7Hülya Apaydın8 İstanbul Üniversitesi-Cerrahpaşa, Cerrahpaşa Tıp Fakültesi, Nöroloji Anabilim Dalı, İstanbul, Türkiye İstanbul Üniversitesi-Cerrahpaşa, Cerrahpaşa Tıp Fakültesi, Nöroloji Anabilim Dalı, İstanbul, Türkiye İstanbul Üniversitesi-Cerrahpaşa, Cerrahpaşa Tıp Fakültesi, Nöroloji Anabilim Dalı, İstanbul, Türkiye İstanbul Üniversitesi-Cerrahpaşa, Cerrahpaşa Tıp Fakültesi, Nöroloji Anabilim Dalı, İstanbul, Türkiye İstanbul Üniversitesi-Cerrahpaşa, Cerrahpaşa Tıp Fakültesi, Nöroloji Anabilim Dalı, İstanbul, Türkiye İstanbul Üniversitesi-Cerrahpaşa, Cerrahpaşa Tıp Fakültesi, Nöroloji Anabilim Dalı, İstanbul, Türkiye İstanbul Üniversitesi-Cerrahpaşa, Cerrahpaşa Tıp Fakültesi, Beyin Cerrahisi Anabilim Dalı, İstanbul, Türkiye İstanbul Üniversitesi-Cerrahpaşa, Cerrahpaşa Tıp Fakültesi, Beyin Cerrahisi Anabilim Dalı, İstanbul, Türkiye İstanbul Üniversitesi-Cerrahpaşa, Cerrahpaşa Tıp Fakültesi, Nöroloji Anabilim Dalı, İstanbul, Türkiye Objective:Deep brain stimulation (DBS) intended to bilateral subthalamic nucleus (STN) used in the Parkinson’s disease (PD) has been reported to lead improved subjective sleep quality, increased sleep efficiency, decreased wakefulness time after sleep, and increased total sleep time. On this basis, we aimed to evaluate the sleep structure and quality by polysomnographic (PSG) investigation parameters in patients diagnosed with idiopathic PD who were planned to undergo bilateral STN-DBS.Materials and Methods:Inclusion criteria were determined as the presence of a clinical diagnosis of idiopathic PD, being 70 years and below, having at least 5 years of disease duration, and being a suitable candidate for STN DBS surgery. Patients were excluded from the study in the presence of dementia or psychiatric disturbances, cardiac pacemaker, and history of cerebrovascular disease. Our study was approved by Local Ethical Committe of Istanbul University-Cerrahpaşa, Cerrahpaşa Faculty of Medicine, and signed consent form was obtained from participants.Results:Eight patients were included in our study; the mean age was calculated as 53.6±4.1 years. When pre- and postoperation PSG parameters were compared, the total sleep time was decreased, however it was not found statistically significant (p=0.840). REM sleep latancy was significantly shortened postoperatively (p=0.003). It was observed that other PSG parameters measuring the macro- and micro-structure of sleep did not change significantly (p>0.050).Conclusion:Many studies have reported substantial improvements in parameters obtained by polysomnography, while only one study has reported that sleep was not normalized although subjective sleep quality was increased. In our study, except for shortening in the REM sleep period, no significant improvement in PSG parameters was observed. The effect of bilateral STB-DBS on sleep is still one of the controversial issues and waits to be demonstrated in the larger series. http://jtsm.org/archives/archive-detail/article-preview/evaluation-of-pre-and-postoperative-polysomnograph/30189 Parkinson’s diseasesubthalamic deep brain stimulationpolysomnography |
| spellingShingle | Nihan Altan Torun Gülçin Benbir Şenel Ayşegül Gündüz Derya Karadeniz Güneş Kızıltan Sibel Ertan Sabri Aydın Selin Yağcı Hülya Apaydın Evaluation of Pre and Postoperative Polysomnographic Data in Patients with Idiopathic Parkinson’s Disease Undergoing Deep Brain Stimulation Intended Bilateral Subthalamic Nucleus Türk Uyku Tıbbı Dergisi Parkinson’s disease subthalamic deep brain stimulation polysomnography |
| title | Evaluation of Pre and Postoperative Polysomnographic Data in Patients with Idiopathic Parkinson’s Disease Undergoing Deep Brain Stimulation Intended Bilateral Subthalamic Nucleus |
| title_full | Evaluation of Pre and Postoperative Polysomnographic Data in Patients with Idiopathic Parkinson’s Disease Undergoing Deep Brain Stimulation Intended Bilateral Subthalamic Nucleus |
| title_fullStr | Evaluation of Pre and Postoperative Polysomnographic Data in Patients with Idiopathic Parkinson’s Disease Undergoing Deep Brain Stimulation Intended Bilateral Subthalamic Nucleus |
| title_full_unstemmed | Evaluation of Pre and Postoperative Polysomnographic Data in Patients with Idiopathic Parkinson’s Disease Undergoing Deep Brain Stimulation Intended Bilateral Subthalamic Nucleus |
| title_short | Evaluation of Pre and Postoperative Polysomnographic Data in Patients with Idiopathic Parkinson’s Disease Undergoing Deep Brain Stimulation Intended Bilateral Subthalamic Nucleus |
| title_sort | evaluation of pre and postoperative polysomnographic data in patients with idiopathic parkinson s disease undergoing deep brain stimulation intended bilateral subthalamic nucleus |
| topic | Parkinson’s disease subthalamic deep brain stimulation polysomnography |
| url |
http://jtsm.org/archives/archive-detail/article-preview/evaluation-of-pre-and-postoperative-polysomnograph/30189
|
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