7α-Hydroxylation of cholestanol by rat liver microsomes

7α-Hydroxylation of cholestanol by rat liver microsomes

In a study of the mechanism whereby 5α-bile acids are formed from cholestanol, the 7α-hydroxylation of cholestanol was investigated in rat liver preparations in vitro. It was found that in the presence of NADPH and oxygen, rat liver microsomes catalyzed the 7α-hydroxylation of cholestanol to the sam...

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Bibliographic Details
Main Authors:	Sarah Shefer, Susan Hauser, Erwin H. Mosbach
Format:	Article
Language:	English
Published:	Elsevier 1968-05-01
Series:	Journal of Lipid Research
Subjects:	7α-hydroxylation in vitro rat liver microsomes cholesterol cholestanol phenobarbital
Online Access:	http://www.sciencedirect.com/science/article/pii/S0022227520430998

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