Identification of Enzymatic Bottlenecks for the Aerobic Production of Malate from Glycerol by the Systematic Gene Overexpression of Anaplerotic Enzymes in <i>Escherichia coli</i>

Identification of Enzymatic Bottlenecks for the Aerobic Production of Malate from Glycerol by the Systematic Gene Overexpression of Anaplerotic Enzymes in <i>Escherichia coli</i>

The biotechnological production of dicarboxylic acids (C4) from renewable carbon sources represents an attractive approach for the provision of these valuable compounds by green chemistry means. Glycerol has become a waste product of the biodiesel industry that serves as a highly reduced carbon sour...

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Bibliographic Details
Main Authors: Zamira E. Soto-Varela, Gema Cabrera, Agustin Romero, Domingo Cantero, Antonio Valle, Jorge Bolivar
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:International Journal of Molecular Sciences
Subjects:
C4 compounds
malate
succinate
glycerol
TCA cycle
anaplerotic enzymes
Online Access:https://www.mdpi.com/1422-0067/22/5/2266

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