Factor H-related protein 1 promotes complement-mediated opsonization of Pseudomonas aeruginosa

Factor H-related protein 1 promotes complement-mediated opsonization of Pseudomonas aeruginosa

Pseudomonas aeruginosa is an important human opportunistic pathogen responsible for a wide range of infections. The complement system is the main early host defense mechanism to control these infections. P. aeruginosa counteracts complement attack by binding Factor H (FH), a complement regulator tha...

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Bibliographic Details
Main Authors: Alex González-Alsina, Héctor Martín-Merinero, Margalida Mateu-Borrás, María Verd, Antonio Doménech-Sánchez, Joanna B. Goldberg, Santiago Rodríguez de Córdoba, Sebastián Albertí
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
FHR-1
factor H
complement system
P. aeruginosa
OprG
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2024.1328185/full

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