Increased risk of aspirin-induced gastric mucosal erosion in elderly Chinese men harboring SLCO1B1*1b/*1b while using aspirin and an ACEI or ARB concomitantly

Increased risk of aspirin-induced gastric mucosal erosion in elderly Chinese men harboring SLCO1B1*1b/*1b while using aspirin and an ACEI or ARB concomitantly

Abstract Background It is well established that long-term use of aspirin can cause gastric mucosal injury. ACEIs and ARBs are inversely related to gastric ulcer development. This study aimed to evaluate the relationship between SLCO1B1 polymorphisms, which can affect ACEI and ARB transport, and gast...

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Bibliographic Details
Main Authors: Lei Duan, Yongyi Bai, Man Li, Huiying Li, Yanping Li, Hongbin Liu
Format: Article
Language:English
Published: BMC 2019-11-01
Series:BMC Medical Genetics
Subjects:
Single nucleotide polymorphism
Aspirin
Gastric mucosa erosion
SLCO1B1
Pharmacogenomics
Online Access:http://link.springer.com/article/10.1186/s12881-019-0918-4

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http://link.springer.com/article/10.1186/s12881-019-0918-4

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