Similarity between the in vitro activity and toxicity of two different fungizone™ / lipofundin™ admixtures Semelhança entre atividade in vitro e toxicidade de duas diferentes misturas de fungizoneä / lipofundinä

Similarity between the in vitro activity and toxicity of two different fungizone™ / lipofundin™ admixtures Semelhança entre atividade in vitro e toxicidade de duas diferentes misturas de fungizoneä / lipofundinä

PURPOSE: Amphotericin B (AmB), an antifungal agent that presents a broad spectrum of activity, remains the gold standard in the antifungal therapy. However, sometimes the high level of toxicity forbids its clinical use. The aim of this work was to evaluate and compare the efficacy and toxicity in vi...

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Bibliographic Details
Main Authors: Ivonete Batista Araújo, C. Ramon N. Brito, Isabel A. Urbano, Victor A. Dominici, Miguel A. Silva Filho, Walteçá L. L. Silveira, Bolívar P. G. L. Damasceno, Aldo Cunha Medeiros, E. Sócrates T. Egito
Format: Article
Language:English
Published: Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia 2005-01-01
Series:Acta Cirúrgica Brasileira
Subjects:
Fungizon™
Lipofundin™
Anfotericina B
Infecção fúngica
Sistemas de liberação de fármacos
Eritrócitos
amphotericin B
Fungal infection
Drug delivery
Red Blood Cells
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502005000700022

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