An insight into the fecal microbiota composition in Romanian patients with ankylosing spondylitis using high-throughput 16S rRNA gene amplicon sequencing
Introduction. Application of next-generation sequencing technology generated a massive amount of information on the gut microbiome composition used to understand its role in the healthy state and in various diseases. We aimed to provide information on the gut microbiota composition of Romanian subje...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Sciendo
2022-01-01
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| Series: | Romanian Journal of Laboratory Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.2478/rrlm-2022-0004 |
| _version_ | 1811254956025446400 |
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| author | Oprea Mihaela Cristea Daniela Dinu Sorin Ciontea Simona Adriana Bojinca Violeta Claudia Predeteanu Denisa Balanescu Andra Rodica Usein Codruta Romanita |
| author_facet | Oprea Mihaela Cristea Daniela Dinu Sorin Ciontea Simona Adriana Bojinca Violeta Claudia Predeteanu Denisa Balanescu Andra Rodica Usein Codruta Romanita |
| author_sort | Oprea Mihaela |
| collection | DOAJ |
| description | Introduction. Application of next-generation sequencing technology generated a massive amount of information on the gut microbiome composition used to understand its role in the healthy state and in various diseases. We aimed to provide information on the gut microbiota composition of Romanian subjects diagnosed with ankylosing spondylitis, an immune-mediated arthropathy linked to a genetic predisposition and gut dysbiosis. |
| first_indexed | 2024-04-12T17:16:27Z |
| format | Article |
| id | doaj.art-f9434ad301fc4e6da5c1efd00fecf960 |
| institution | Directory Open Access Journal |
| issn | 2284-5623 |
| language | English |
| last_indexed | 2024-04-12T17:16:27Z |
| publishDate | 2022-01-01 |
| publisher | Sciendo |
| record_format | Article |
| series | Romanian Journal of Laboratory Medicine |
| spelling | doaj.art-f9434ad301fc4e6da5c1efd00fecf9602022-12-22T03:23:38ZengSciendoRomanian Journal of Laboratory Medicine2284-56232022-01-01301496110.2478/rrlm-2022-0004An insight into the fecal microbiota composition in Romanian patients with ankylosing spondylitis using high-throughput 16S rRNA gene amplicon sequencingOprea Mihaela0Cristea Daniela1Dinu Sorin2Ciontea Simona Adriana3Bojinca Violeta Claudia4Predeteanu Denisa5Balanescu Andra Rodica6Usein Codruta Romanita7Molecular Epidemiology for Communicable Diseases Laboratory, “Cantacuzino” National Military Medical Institute for Research and Development, Bucharest, RomaniaEnteric Bacterial Infections Laboratory, “Cantacuzino” National Military Medical Institute for Research and Development, Bucharest, RomaniaMolecular Epidemiology for Communicable Diseases Laboratory, “Cantacuzino” National Military Medical Institute for Research and Development, Bucharest, RomaniaEnteric Bacterial Infections Laboratory, “Cantacuzino” National Military Medical Institute for Research and Development, Bucharest, RomaniaDepartment of Internal Medicine and Rheumatology, “Sf. Maria” Clinical Hospital, Bucharest, RomaniaDepartment of Internal Medicine and Rheumatology, “Sf. Maria” Clinical Hospital, Bucharest, RomaniaDepartment of Internal Medicine and Rheumatology, “Sf. Maria” Clinical Hospital, Bucharest, RomaniaMolecular Epidemiology for Communicable Diseases Laboratory, “Cantacuzino” National Military Medical Institute for Research and Development, Bucharest, RomaniaIntroduction. Application of next-generation sequencing technology generated a massive amount of information on the gut microbiome composition used to understand its role in the healthy state and in various diseases. We aimed to provide information on the gut microbiota composition of Romanian subjects diagnosed with ankylosing spondylitis, an immune-mediated arthropathy linked to a genetic predisposition and gut dysbiosis.https://doi.org/10.2478/rrlm-2022-0004ankylosing spondylitisnext generation sequencinggut microbiome16s rrna amplicon sequencing |
| spellingShingle | Oprea Mihaela Cristea Daniela Dinu Sorin Ciontea Simona Adriana Bojinca Violeta Claudia Predeteanu Denisa Balanescu Andra Rodica Usein Codruta Romanita An insight into the fecal microbiota composition in Romanian patients with ankylosing spondylitis using high-throughput 16S rRNA gene amplicon sequencing Romanian Journal of Laboratory Medicine ankylosing spondylitis next generation sequencing gut microbiome 16s rrna amplicon sequencing |
| title | An insight into the fecal microbiota composition in Romanian patients with ankylosing spondylitis using high-throughput 16S rRNA gene amplicon sequencing |
| title_full | An insight into the fecal microbiota composition in Romanian patients with ankylosing spondylitis using high-throughput 16S rRNA gene amplicon sequencing |
| title_fullStr | An insight into the fecal microbiota composition in Romanian patients with ankylosing spondylitis using high-throughput 16S rRNA gene amplicon sequencing |
| title_full_unstemmed | An insight into the fecal microbiota composition in Romanian patients with ankylosing spondylitis using high-throughput 16S rRNA gene amplicon sequencing |
| title_short | An insight into the fecal microbiota composition in Romanian patients with ankylosing spondylitis using high-throughput 16S rRNA gene amplicon sequencing |
| title_sort | insight into the fecal microbiota composition in romanian patients with ankylosing spondylitis using high throughput 16s rrna gene amplicon sequencing |
| topic | ankylosing spondylitis next generation sequencing gut microbiome 16s rrna amplicon sequencing |
| url | https://doi.org/10.2478/rrlm-2022-0004 |
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