Oxidative Stability and Protective Effect of the Mixture between <i>Helianthus annuus</i> L. and <i>Oenothera biennis</i> L. Oils on 3D Tissue Models of Skin Irritation and Phototoxicity
The present study was aimed to evaluate the oxidative stability as well as to assess the protective effect of the mixture of <i>Helianthus annuus</i> L. (HAO) and <i>Oenothera biennis</i> L. (OBO) oils on 3D tissue models of skin irritation and phototoxicity. The following me...
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MDPI AG
2022-11-01
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| Online Access: | https://www.mdpi.com/2223-7747/11/21/2977 |
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| author | Ramona Fecker Ioana Zinuca Magyari-Pavel Ileana Cocan Ersilia Alexa Iuliana Maria Popescu Adelina Lombrea Larisa Bora Cristina Adriana Dehelean Valentina Buda Roxana Folescu Corina Danciu |
| author_facet | Ramona Fecker Ioana Zinuca Magyari-Pavel Ileana Cocan Ersilia Alexa Iuliana Maria Popescu Adelina Lombrea Larisa Bora Cristina Adriana Dehelean Valentina Buda Roxana Folescu Corina Danciu |
| author_sort | Ramona Fecker |
| collection | DOAJ |
| description | The present study was aimed to evaluate the oxidative stability as well as to assess the protective effect of the mixture of <i>Helianthus annuus</i> L. (HAO) and <i>Oenothera biennis</i> L. (OBO) oils on 3D tissue models of skin irritation and phototoxicity. The following methods were used: GS analysis (fatty acids composition), thiobarbituric acid-reactive substances assay (TBA) (lipid oxidation degree of tested samples), 3D EpiDerm models (skin irritation and phototoxicity). For HAO the detected saturated fatty acids (SFA) were palmitic acid (7.179%), stearic acid (3.586%), eicosanoic (0.138%) and docosanoic acid (0.548%) The monounsaturated acids (MUFA) were palmitoleic acid (0.158%) and oleic acid (28.249%) and the polyunsaturated acids (PUFA) were linoleic acid (59.941%) and linolenic acid (0.208%). For OBO the detected SFA were myristic acid (0.325%), pentadecylic acid (0.281%), palmitic (7.2%), stearic (2.88%), and arachidic acid (0.275%). Regarding MUFA, even a lower proportion (8.196%) was observed, predominantly being oleic acid, cis form (7.175%), oleic (n10) (0.558%) and 11-eicosenoic (0.210%) acids. The higher content was found for PUFA (82.247%), the most significant proportions being linoleic acid (72.093%), arachidonic acid (9.812%) and linolenic (0.233%). Obtained data indicate a good oxidative stability and biocompatibility of the mixture on the 3D EpiDerm models with no irritant and no phototoxic effects. <i>Oenothera biennis</i> L. oil may be an excellent natural choice in order to delay or prevent oxidative damage of <i>Helianthus annuus</i> L. oil. |
| first_indexed | 2024-03-09T18:44:37Z |
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| last_indexed | 2024-03-09T18:44:37Z |
| publishDate | 2022-11-01 |
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| series | Plants |
| spelling | doaj.art-f943607db58c4e52bd3a6b5029765ad02023-11-24T06:26:13ZengMDPI AGPlants2223-77472022-11-011121297710.3390/plants11212977Oxidative Stability and Protective Effect of the Mixture between <i>Helianthus annuus</i> L. and <i>Oenothera biennis</i> L. Oils on 3D Tissue Models of Skin Irritation and PhototoxicityRamona Fecker0Ioana Zinuca Magyari-Pavel1Ileana Cocan2Ersilia Alexa3Iuliana Maria Popescu4Adelina Lombrea5Larisa Bora6Cristina Adriana Dehelean7Valentina Buda8Roxana Folescu9Corina Danciu10Department of Pharmacognosy, Faculty of Pharmacy, “Victor Babes” University of Medicine and Pharmacy Timisoara, Eftimie Murgu Square No. 2, 00041 Timişoara, RomaniaDepartment of Pharmacognosy, Faculty of Pharmacy, “Victor Babes” University of Medicine and Pharmacy Timisoara, Eftimie Murgu Square No. 2, 00041 Timişoara, RomaniaFaculty of Food Engineering, University of Life Sciences “King Michael I” from Timisoara, Calea Aradului 119, 300645 Timisoara, RomaniaFaculty of Food Engineering, University of Life Sciences “King Michael I” from Timisoara, Calea Aradului 119, 300645 Timisoara, RomaniaFaculty of Agriculture, University of Life Sciences “King Michael I” from Timisoara, Calea Aradului 119, 300645 Timisoara, RomaniaDepartment of Pharmacognosy, Faculty of Pharmacy, “Victor Babes” University of Medicine and Pharmacy Timisoara, Eftimie Murgu Square No. 2, 00041 Timişoara, RomaniaDepartment of Pharmacognosy, Faculty of Pharmacy, “Victor Babes” University of Medicine and Pharmacy Timisoara, Eftimie Murgu Square No. 2, 00041 Timişoara, RomaniaResearch Center for Pharmaco-Toxicological Evaluations, Faculty of Pharmacy, “Victor Babes” University of Medicine and Pharmacy Timisoara, Eftimie Murgu Square No. 2, 300041 Timişoara, RomaniaResearch Center for Pharmaco-Toxicological Evaluations, Faculty of Pharmacy, “Victor Babes” University of Medicine and Pharmacy Timisoara, Eftimie Murgu Square No. 2, 300041 Timişoara, RomaniaDepartment of Balneology, Medical Recovery and Rheumatology, Family Discipline, Center for Preventive Medicine, Center for Advanced Research in Cardiovascular Pathology and Hemostaseology, “Victor Babes” University of Medicine and Pharmacy Timisoara, Eftimie Murgu Square No. 2, 300041 Timişoara, RomaniaDepartment of Pharmacognosy, Faculty of Pharmacy, “Victor Babes” University of Medicine and Pharmacy Timisoara, Eftimie Murgu Square No. 2, 00041 Timişoara, RomaniaThe present study was aimed to evaluate the oxidative stability as well as to assess the protective effect of the mixture of <i>Helianthus annuus</i> L. (HAO) and <i>Oenothera biennis</i> L. (OBO) oils on 3D tissue models of skin irritation and phototoxicity. The following methods were used: GS analysis (fatty acids composition), thiobarbituric acid-reactive substances assay (TBA) (lipid oxidation degree of tested samples), 3D EpiDerm models (skin irritation and phototoxicity). For HAO the detected saturated fatty acids (SFA) were palmitic acid (7.179%), stearic acid (3.586%), eicosanoic (0.138%) and docosanoic acid (0.548%) The monounsaturated acids (MUFA) were palmitoleic acid (0.158%) and oleic acid (28.249%) and the polyunsaturated acids (PUFA) were linoleic acid (59.941%) and linolenic acid (0.208%). For OBO the detected SFA were myristic acid (0.325%), pentadecylic acid (0.281%), palmitic (7.2%), stearic (2.88%), and arachidic acid (0.275%). Regarding MUFA, even a lower proportion (8.196%) was observed, predominantly being oleic acid, cis form (7.175%), oleic (n10) (0.558%) and 11-eicosenoic (0.210%) acids. The higher content was found for PUFA (82.247%), the most significant proportions being linoleic acid (72.093%), arachidonic acid (9.812%) and linolenic (0.233%). Obtained data indicate a good oxidative stability and biocompatibility of the mixture on the 3D EpiDerm models with no irritant and no phototoxic effects. <i>Oenothera biennis</i> L. oil may be an excellent natural choice in order to delay or prevent oxidative damage of <i>Helianthus annuus</i> L. oil.https://www.mdpi.com/2223-7747/11/21/2977<i>Oenothera biennis</i> L. oil<i>Helianthus annuus</i> L. oilskin irritationphototoxicity3D tissue models |
| spellingShingle | Ramona Fecker Ioana Zinuca Magyari-Pavel Ileana Cocan Ersilia Alexa Iuliana Maria Popescu Adelina Lombrea Larisa Bora Cristina Adriana Dehelean Valentina Buda Roxana Folescu Corina Danciu Oxidative Stability and Protective Effect of the Mixture between <i>Helianthus annuus</i> L. and <i>Oenothera biennis</i> L. Oils on 3D Tissue Models of Skin Irritation and Phototoxicity Plants <i>Oenothera biennis</i> L. oil <i>Helianthus annuus</i> L. oil skin irritation phototoxicity 3D tissue models |
| title | Oxidative Stability and Protective Effect of the Mixture between <i>Helianthus annuus</i> L. and <i>Oenothera biennis</i> L. Oils on 3D Tissue Models of Skin Irritation and Phototoxicity |
| title_full | Oxidative Stability and Protective Effect of the Mixture between <i>Helianthus annuus</i> L. and <i>Oenothera biennis</i> L. Oils on 3D Tissue Models of Skin Irritation and Phototoxicity |
| title_fullStr | Oxidative Stability and Protective Effect of the Mixture between <i>Helianthus annuus</i> L. and <i>Oenothera biennis</i> L. Oils on 3D Tissue Models of Skin Irritation and Phototoxicity |
| title_full_unstemmed | Oxidative Stability and Protective Effect of the Mixture between <i>Helianthus annuus</i> L. and <i>Oenothera biennis</i> L. Oils on 3D Tissue Models of Skin Irritation and Phototoxicity |
| title_short | Oxidative Stability and Protective Effect of the Mixture between <i>Helianthus annuus</i> L. and <i>Oenothera biennis</i> L. Oils on 3D Tissue Models of Skin Irritation and Phototoxicity |
| title_sort | oxidative stability and protective effect of the mixture between i helianthus annuus i l and i oenothera biennis i l oils on 3d tissue models of skin irritation and phototoxicity |
| topic | <i>Oenothera biennis</i> L. oil <i>Helianthus annuus</i> L. oil skin irritation phototoxicity 3D tissue models |
| url | https://www.mdpi.com/2223-7747/11/21/2977 |
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