Carbohydrate Maldigestion and Intolerance
This review summarizes dietary carbohydrate intolerance conditions and recent advances on the possible role of carbohydrate maldigestion and dietary outcomes in patients with functional bowel disease. When malabsorbed carbohydrates reach the colon, they are fermented by colonic bacteria, with the pr...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-05-01
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| Series: | Nutrients |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2072-6643/14/9/1923 |
| _version_ | 1797503416293916672 |
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| author | Fernando Fernández-Bañares |
| author_facet | Fernando Fernández-Bañares |
| author_sort | Fernando Fernández-Bañares |
| collection | DOAJ |
| description | This review summarizes dietary carbohydrate intolerance conditions and recent advances on the possible role of carbohydrate maldigestion and dietary outcomes in patients with functional bowel disease. When malabsorbed carbohydrates reach the colon, they are fermented by colonic bacteria, with the production of short-chain fatty acids and gas lowering colonic pH. The appearance of diarrhoea or symptoms of flatulence depends in part on the balance between the production and elimination of these fermentation products. Different studies have shown that there are no differences in the frequency of sugar malabsorption between patients with irritable bowel disease (IBS) and healthy controls; however, the severity of symptoms after a sugar challenge is higher in patients than in controls. A diet low in ‘Fermentable, Oligo-Di- and Monosaccharides and Polyols’ (FODMAPs) is an effective treatment for global symptoms and abdominal pain in IBS, but its implementation should be supervised by a trained dietitian. A ‘bottom-up’ approach to the low-FODMAP diet has been suggested to avoid an alteration of gut microbiota and nutritional status. Two approaches have been suggested in this regard: starting with only certain subgroups of the low-FODMAP diet based on dietary history or with a gluten-free diet. |
| first_indexed | 2024-03-10T03:50:19Z |
| format | Article |
| id | doaj.art-f945eeae628e449681493bdec4a85205 |
| institution | Directory Open Access Journal |
| issn | 2072-6643 |
| language | English |
| last_indexed | 2024-03-10T03:50:19Z |
| publishDate | 2022-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nutrients |
| spelling | doaj.art-f945eeae628e449681493bdec4a852052023-11-23T09:00:24ZengMDPI AGNutrients2072-66432022-05-01149192310.3390/nu14091923Carbohydrate Maldigestion and IntoleranceFernando Fernández-Bañares0Department of Gastroenterology, Hospital Universitary MútuaTerrassa, 08221 Terrassa, SpainThis review summarizes dietary carbohydrate intolerance conditions and recent advances on the possible role of carbohydrate maldigestion and dietary outcomes in patients with functional bowel disease. When malabsorbed carbohydrates reach the colon, they are fermented by colonic bacteria, with the production of short-chain fatty acids and gas lowering colonic pH. The appearance of diarrhoea or symptoms of flatulence depends in part on the balance between the production and elimination of these fermentation products. Different studies have shown that there are no differences in the frequency of sugar malabsorption between patients with irritable bowel disease (IBS) and healthy controls; however, the severity of symptoms after a sugar challenge is higher in patients than in controls. A diet low in ‘Fermentable, Oligo-Di- and Monosaccharides and Polyols’ (FODMAPs) is an effective treatment for global symptoms and abdominal pain in IBS, but its implementation should be supervised by a trained dietitian. A ‘bottom-up’ approach to the low-FODMAP diet has been suggested to avoid an alteration of gut microbiota and nutritional status. Two approaches have been suggested in this regard: starting with only certain subgroups of the low-FODMAP diet based on dietary history or with a gluten-free diet.https://www.mdpi.com/2072-6643/14/9/1923sugar malabsorptionlactosefructosesorbitolsucroseFODMAP |
| spellingShingle | Fernando Fernández-Bañares Carbohydrate Maldigestion and Intolerance Nutrients sugar malabsorption lactose fructose sorbitol sucrose FODMAP |
| title | Carbohydrate Maldigestion and Intolerance |
| title_full | Carbohydrate Maldigestion and Intolerance |
| title_fullStr | Carbohydrate Maldigestion and Intolerance |
| title_full_unstemmed | Carbohydrate Maldigestion and Intolerance |
| title_short | Carbohydrate Maldigestion and Intolerance |
| title_sort | carbohydrate maldigestion and intolerance |
| topic | sugar malabsorption lactose fructose sorbitol sucrose FODMAP |
| url | https://www.mdpi.com/2072-6643/14/9/1923 |
| work_keys_str_mv | AT fernandofernandezbanares carbohydratemaldigestionandintolerance |