Masked arterial hypertension: prevalence, pathophysiological determinants and clinical significance
In most modern studies, masked arterial hypertension (MAH) is characterized as a poorly diagnosed, latent clinical condition predisposing to subclinical damage to target organs and an increased risk of cardiovascular complications. The prevalence of MAH among the population depends on gender, age, a...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | Russian |
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«FIRMA «SILICEA» LLC
2019-09-01
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| Series: | Российский кардиологический журнал |
| Subjects: | |
| Online Access: | https://russjcardiol.elpub.ru/jour/article/view/3147 |
| _version_ | 1797856853924773888 |
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| author | В. I. Geltser V. N. Kotelnikov О. О. Vetrova R. S. Karpov |
| author_facet | В. I. Geltser V. N. Kotelnikov О. О. Vetrova R. S. Karpov |
| author_sort | В. I. Geltser |
| collection | DOAJ |
| description | In most modern studies, masked arterial hypertension (MAH) is characterized as a poorly diagnosed, latent clinical condition predisposing to subclinical damage to target organs and an increased risk of cardiovascular complications. The prevalence of MAH among the population depends on gender, age, anthropometric and socioeconomic factors, profession, race and other characteristics. The most important risk factors (RF) of MAH and its pathophysiological determinants include genetic polymorphism, subclinical non-specific inflammation, hemostatic disorders, obesity, metabolic syndrome, water-salt imbalance, dyslipidemia, hyperuricemia. A defined value has latent dysfunction of the mechanisms that provide circulatory homeostasis, the detection of which is possible by the hemodynamic response to psycho-emotional, hypoxic, hypocapnic, orthostatic effects. Aggressiveness of RF exposure and the consequences of their implementation are evaluated by the rate of development of cardiovascular events and mortality, which indicate an unfavorable prognosis of “uncontrolled” MAH. The maximum reduction of the RF effects and rational pharmacotherapy can significantly improve its clinical prospects. |
| first_indexed | 2024-04-09T20:47:09Z |
| format | Article |
| id | doaj.art-f94a098e10214781972a51fd28630841 |
| institution | Directory Open Access Journal |
| issn | 1560-4071 2618-7620 |
| language | Russian |
| last_indexed | 2024-04-09T20:47:09Z |
| publishDate | 2019-09-01 |
| publisher | «FIRMA «SILICEA» LLC |
| record_format | Article |
| series | Российский кардиологический журнал |
| spelling | doaj.art-f94a098e10214781972a51fd286308412023-03-29T21:23:32Zrus«FIRMA «SILICEA» LLCРоссийский кардиологический журнал1560-40712618-76202019-09-0109929810.15829/1560-4071-2019-9-92-982590Masked arterial hypertension: prevalence, pathophysiological determinants and clinical significanceВ. I. Geltser0V. N. Kotelnikov1О. О. Vetrova2R. S. Karpov3Far Eastern Federal UniversityFar Eastern Federal UniversityFar Eastern Federal UniversityTomsk National Research Medical CenterIn most modern studies, masked arterial hypertension (MAH) is characterized as a poorly diagnosed, latent clinical condition predisposing to subclinical damage to target organs and an increased risk of cardiovascular complications. The prevalence of MAH among the population depends on gender, age, anthropometric and socioeconomic factors, profession, race and other characteristics. The most important risk factors (RF) of MAH and its pathophysiological determinants include genetic polymorphism, subclinical non-specific inflammation, hemostatic disorders, obesity, metabolic syndrome, water-salt imbalance, dyslipidemia, hyperuricemia. A defined value has latent dysfunction of the mechanisms that provide circulatory homeostasis, the detection of which is possible by the hemodynamic response to psycho-emotional, hypoxic, hypocapnic, orthostatic effects. Aggressiveness of RF exposure and the consequences of their implementation are evaluated by the rate of development of cardiovascular events and mortality, which indicate an unfavorable prognosis of “uncontrolled” MAH. The maximum reduction of the RF effects and rational pharmacotherapy can significantly improve its clinical prospects.https://russjcardiol.elpub.ru/jour/article/view/3147masked arterial hypertensionprevalencerisk factorsclinical significance |
| spellingShingle | В. I. Geltser V. N. Kotelnikov О. О. Vetrova R. S. Karpov Masked arterial hypertension: prevalence, pathophysiological determinants and clinical significance Российский кардиологический журнал masked arterial hypertension prevalence risk factors clinical significance |
| title | Masked arterial hypertension: prevalence, pathophysiological determinants and clinical significance |
| title_full | Masked arterial hypertension: prevalence, pathophysiological determinants and clinical significance |
| title_fullStr | Masked arterial hypertension: prevalence, pathophysiological determinants and clinical significance |
| title_full_unstemmed | Masked arterial hypertension: prevalence, pathophysiological determinants and clinical significance |
| title_short | Masked arterial hypertension: prevalence, pathophysiological determinants and clinical significance |
| title_sort | masked arterial hypertension prevalence pathophysiological determinants and clinical significance |
| topic | masked arterial hypertension prevalence risk factors clinical significance |
| url | https://russjcardiol.elpub.ru/jour/article/view/3147 |
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