A new class of polyphenolic carbosilane dendrimers binds human serum albumin in a structure-dependent fashion

A new class of polyphenolic carbosilane dendrimers binds human serum albumin in a structure-dependent fashion

Abstract The use of dendrimers as drug and nucleic acid delivery systems requires knowledge of their interactions with objects on their way to the target. In the present work, we investigated the interaction of a new class of carbosilane dendrimers functionalized with polyphenolic and caffeic acid r...

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Bibliographic Details
Main Authors: Marika Grodzicka, Sylwia Michlewska, Adam Buczkowski, Szymon Sekowski, Cornelia E. Pena-Gonzalez, Paula Ortega, Francisco Javier de la Mata, Janusz Blasiak, Maria Bryszewska, Maksim Ionov
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Series:Scientific Reports
Subjects:
Polyphenolic dendrimers
Serum human albumin
Zeta potential
Circular dichroism
Isothermal titration calorimetry
Online Access:https://doi.org/10.1038/s41598-024-56509-0

Internet

https://doi.org/10.1038/s41598-024-56509-0

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