JianPiYiShen formula prevents cisplatin-induced acute kidney injury in mice by improving necroptosis through MAPK pathway

JianPiYiShen formula prevents cisplatin-induced acute kidney injury in mice by improving necroptosis through MAPK pathway

Abstract Background Acute kidney injury (AKI), characterized by necroptosis and activation of MAPK pathway, causes sudden declines in renal function. To date, efficacious treatments are lacking. JianPiYiShen Formula (JPYSF) has a protective effect on the kidneys. The aim of this study is to explore...

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Bibliographic Details
Main Authors: Zhongtang Li, Riming He, Jiahui Liu, Xiaoming Jin, Beibei Jiang, Yunlan Lao, Shudong Yang
Format: Article
Language:English
Published: BMC 2024-02-01
Series:BMC Complementary Medicine and Therapies
Subjects:
Acute kidney injury
Cisplatin
JianPiYiShen formula
MAPK pathway
Necroptosis
Online Access:https://doi.org/10.1186/s12906-024-04366-9

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